Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 1/20 | 0.60 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8371630 | 0.89 | S100A4 (0.64) | S100A4MALT1HIF1ACHRNA7CFTR | |
| SCHEMBL12181932 | 0.76 | S100A4 (1.00) | S100A4MALT1HRH3 | |
| SCHEMBL8368796 | 0.74 | S100A4 (0.58) | S100A4MALT1HRH3MKNK1ACP1 | |
| SCHEMBL23406015 | 0.74 | HRH3 (0.47) | S100A4HIF1ACHRNA7CFTRHRH3 | |
| SCHEMBL29743920 | 0.74 | HRH3 (0.47) | S100A4HIF1ACHRNA7CFTRHRH3 | |
| SCHEMBL29743857 | 0.73 | HRH3 (0.49) | S100A4CHRNA7CFTRHRH3MKNK1 | |
| SCHEMBL23405936 | 0.73 | HRH3 (0.49) | S100A4CHRNA7CFTRHRH3MKNK1 | |
| SCHEMBL23405983 | 0.72 | CHRNA7 (0.51) | S100A4HIF1ACHRNA7CFTRHRH3 | |
| SCHEMBL29743798 | 0.72 | CHRNA7 (0.51) | S100A4HIF1ACHRNA7CFTRHRH3 | |
| SCHEMBL8371714 | 0.72 | S100A4 (0.59) | S100A4MALT1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999052365-A1 | ANTICANCER AGENTS | ELI LILLY AND COMPANY (US) | 1999-10-21 | — | — | WO | disclosed |