Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 1/20 | 0.58 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.57 |
| ▸ | ACP1 | P24666 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8368881 | 0.94 | S100A4 (0.49) | S100A4MALT1ACP1ALDH1A1MEN1 | |
| SCHEMBL8370523 | 0.93 | S100A4 (0.51) | S100A4MALT1ACP1ALDH1A1MEN1 | |
| SCHEMBL8367269 | 0.86 | MALT1 (0.60) | S100A4MALT1ALDH1A1MEN1KMT2A | |
| SCHEMBL8371630 | 0.81 | S100A4 (0.64) | S100A4MALT1ACP1HRH3MKNK1 | |
| SCHEMBL8370510 | 0.79 | S100A4 (0.46) | S100A4ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL1917262 | 0.78 | S100A4 (0.45) | S100A4MALT1ACP1ALDH1A1KDM4E | |
| SCHEMBL1918660 | 0.78 | S100A4 (0.45) | S100A4MALT1ACP1ALDH1A1MEN1 | |
| SCHEMBL8368655 | 0.76 | MALT1 (0.41) | S100A4MALT1ALDH1A1MEN1KMT2A | |
| SCHEMBL8368658 | 0.75 | S100A4 (0.44) | S100A4MALT1ALDH1A1MEN1KMT2A | |
| SCHEMBL8368651 | 0.74 | S100A4 (0.60) | S100A4MALT1ACP1HRH3MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999052365-A1 | ANTICANCER AGENTS | ELI LILLY AND COMPANY (US) | 1999-10-21 | — | — | WO | disclosed |