SCHEMBL8368707

SCHEMBL8368707

CC(CC(c1ccccc1)c1cc(S(=O)(=O)O)cc(O)c1O)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 4/20 0.40
HKDC1 Q2TB90 1/20 0.36
NSD2 O96028 1/20 0.35
DUSP3 P51452 1/20 0.35
PTPN5 P54829 1/20 0.35
CASP7 P55210 1/20 0.35
CASP6 P55212 1/20 0.35
PTPN11 Q06124 1/20 0.35
TSHR P16473 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
ALDH1A1 P00352 2/20 0.34
HSD17B10 Q99714 2/20 0.34
GAA P10253 1/20 0.34
HTT P42858 1/20 0.34
LMNA P02545 1/20 0.34
ESR1 P03372 1/20 0.34
CHRM2 P08172 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8368715 0.87 TRPA1 (0.38) TRPA1HKDC1TSHRSMN1; SMN2HDAC4
SCHEMBL8365844 0.86 TRPA1 (0.40) TRPA1TSHRSMN1; SMN2HTTLMNA
SCHEMBL8365859 0.82 TRPA1 (0.43) TRPA1TSHRHDAC4HDAC2HDAC8
SCHEMBL8365895 0.82 TYR (0.47) HKDC1NSD2DUSP3PTPN5CASP7
SCHEMBL8516413 0.81 MAPT (0.36) TRPA1SMN1; SMN2HDAC4HDAC2HDAC8
SCHEMBL8370432 0.80 TYR (0.45) HKDC1NSD2DUSP3PTPN5CASP7
SCHEMBL8367586 0.79 TRPA1 (0.40) TRPA1TSHRSMN1; SMN2ALDH1A1GAA
SCHEMBL8370514 0.79 TRPA1 (0.40) TRPA1TSHRHDAC4HDAC2HDAC8
SCHEMBL8368698 0.78 TRPA1 (0.42) TRPA1ALDH1A1LMNAESR1CHRM2
SCHEMBL8368243 0.78 TRPA1 (0.39) TRPA1TSHRALDH1A1LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714785-B1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI CHEMICALS INC (JP) 1999-01-07 EP disclosed
US-5647896-A MULTIVALENT SALT OF A SALICYLIC ACID DERIVATIVE, SULFONATED PHENOL MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-15 US disclosed
EP-0714785-A1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-06-05 EP disclosed