Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11053752 | 0.78 | KDM4E (0.64) | KDM4ELMNAUSP2KMT2AMEN1 | |
| SCHEMBL27982657 | 0.77 | KDM4E (0.61) | KDM4ELMNAUSP2KMT2AMEN1 | |
| SCHEMBL16401492 | 0.77 | KDM4E (0.61) | KDM4ELMNAUSP2KMT2AMEN1 | |
| SCHEMBL14032323 | 0.76 | KDM4E (1.00) | KDM4ELMNAUSP2KMT2AMEN1 | |
| SCHEMBL11637797 | 0.75 | KDM4E (0.77) | KDM4ELMNAUSP2KMT2AMEN1 | |
| SCHEMBL4614217 | 0.73 | KDM4E (0.53) | KDM4ELMNAUSP2KMT2AMEN1 | |
| SCHEMBL7091674 | 0.73 | KDM4E (0.36) | KDM4ELMNAUSP2KMT2AMEN1 | |
| SCHEMBL7061378 | 0.72 | KDM4E (0.50) | KDM4ELMNAUSP2KMT2AMEN1 | |
| SCHEMBL17949841 | 0.72 | KDM4E (0.60) | KDM4ELMNAUSP2KMT2AMEN1 | |
| SCHEMBL11668101 | 0.70 | KDM4E (1.00) | KDM4ELMNAUSP2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190070165-A1 | N-HYDROXYISOQUINOLINEDIONE INHIBITORS OF HBV REPLICATION | SAINT LOUIS UNIVERSITY (US) | 2019-03-07 | — | — | US | disclosed |
| EP-0823069-B1 | IMAGE-RECORDING ELEMENT | POLAROID CORP (US) | 1999-06-02 | — | — | EP | disclosed |
| EP-0510440-B1 | Positive-working radiation-sensitive composition and radiation-sensitive recording material produced therewith | CLARIANT GMBH (DE) | 1999-01-13 | — | — | EP | disclosed |
| US-5667933-A | PHOTOSENSITIVE IMAGES RECORDING ELEMENTS FOR THERMAL IMAGES | POLAROID CORPORATION (US) | 1997-09-16 | — | — | US | disclosed |
| EP-0510443-B1 | Negative-working radiation-sensitive composition and radiation-sensitive recording material produced therewith | HOECHST AG (DE) | 1995-03-22 | — | — | EP | disclosed |
| US-5230985-A | NEGATIVE-WORKING RADIATION-SENSITIVE MIXTURES, AND RADIATION-SENSITIVE RECORDING MATERIAL PRODUCED WITH THESE MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-27 | — | — | US | disclosed |
| US-5229254-A | Photoresists, printing plates, sulfonic acid generators | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-20 | — | — | US | disclosed |
| EP-0510443-A1 | Negative-working radiation-sensitive composition and radiation-sensitive recording material produced therewith | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-28 | — | — | EP | disclosed |
| EP-0510440-A1 | Positive-working radiation-sensitive composition and radiation-sensitive recording material produced therewith | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190070165-A1 | N-HYDROXYISOQUINOLINEDIONE INHIBITORS OF HBV REPLICATION | HCCS, HAVCR2, HDGF | KDM4E 1221/4885LMNA 1966/4885USP2 1983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.