SCHEMBL4614217

SCHEMBL4614217

Cc1cc(O)n(C)c(=O)c1C#N

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 13/20 0.53
USP2 O75604 1/20 0.53
LMNA P02545 4/20 0.51
MEN1 O00255 5/20 0.49
KMT2A Q03164 5/20 0.49
UPP1 Q16831 1/20 0.49
MAPT P10636 4/20 0.46
HPGD P15428 1/20 0.46
THRB P10828 1/20 0.44
HSD17B10 Q99714 2/20 0.43
ALDH1A1 P00352 3/20 0.43
MAPK1 P28482 1/20 0.43
TSHR P16473 1/20 0.42
RAB9A P51151 1/20 0.42
TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17949841 0.83 KDM4E (0.60) KDM4EUSP2LMNAMEN1KMT2A
SCHEMBL11053752 0.82 KDM4E (0.64) KDM4EUSP2LMNAMEN1KMT2A
SCHEMBL6562559 0.81 KDM4E (0.54) KDM4EUSP2LMNAMEN1KMT2A
SCHEMBL10769714 0.80 KDM4E (0.57) KDM4EUSP2LMNAMEN1KMT2A
SCHEMBL10766144 0.80 KDM4E (0.57) KDM4EUSP2LMNAMEN1KMT2A
SCHEMBL7061378 0.79 KDM4E (0.50) KDM4EUSP2LMNAMEN1KMT2A
SCHEMBL4801776 0.79 KDM4E (0.68) KDM4EUSP2LMNAMEN1KMT2A
SCHEMBL6136816 0.79 KDM4E (0.73) KDM4EUSP2LMNAMEN1KMT2A
SCHEMBL10768477 0.79 KDM4E (0.56) KDM4EUSP2LMNAMEN1KMT2A
SCHEMBL7063849 0.78 KDM4E (0.49) KDM4EUSP2LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 289 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025107145-A1 CONTINUOUS SYNTHESIS METHOD FOR DISPERSE YELLOW DYE 乐平市赛复乐医药化工有限公司 2025-05-30 WO claimed
CN-118727475-B Room temperature salt-free rapid reactive dyeing and recycling method suitable for cellulose fibers 绍兴劲草化工有限公司 2025-04-29 CN claimed
CN-118727475-A Room temperature salt-free rapid reactive dyeing and recycling method suitable for cellulose fibers 绍兴劲草化工有限公司 2024-10-01 CN claimed
CN-112778793-A Pyridone dispersed orange yellow dye composition and fabric dyeing process thereof 邓生平 2021-05-11 CN claimed
CN-111138885-A Preparation method of nitrobenzoisothiazole-pyridine dye with good acid-base stability 常州工学院 2020-05-12 CN claimed
US-7429274-B2 Agent and method for the oxidative coloring of keratin fibers WELLA AG (DE) 2008-09-30 US claimed
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative L'OREAL S.A. 2007-06-14 US claimed
US-7204857-B1 Dyeing method using a specific active methylene compound and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative L'OREAL S.A. (FR) 2007-04-17 US claimed
US-20070079452-A1 Agent and method for the oxidative coloring of keratin fibers Wella GmbH (DE) 2007-04-12 US claimed
EP-1699426-A1 AGENT AND METHOD FOR OXIDATIVELY DYEING KERATIN FIBERS Wella Aktiengesellschaft (DE) 2006-09-13 EP claimed
EP-1362579-B1 Agent for dyeing keratinous fibres HENKEL KGAA (DE) 2006-05-24 EP claimed
EP-1300135-B1 Agent for dyeing keratinous fibres comprising 2-aryliden-indolin-3-one derivatives HENKEL KGAA (DE) 2006-05-03 EP claimed
WO-2005060927-A1 AGENT AND METHOD FOR OXIDATIVELY DYEING KERATIN FIBERS WELLA AKTIENGESELLSCHAFT (DE) 2005-07-07 WO claimed
EP-1433785-A1 Agents for the coloration of keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2004-06-30 EP claimed
EP-1362579-A1 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-11-19 EP claimed
EP-1300132-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
EP-1300135-A1 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
JP-10183005-A None JP disclosed
US-3966703-A Asymmetrical frisazo dyestuffs derived from diazotized 2,7-diamino-carbazole BAYER AKTIENGESELLSCHAFT (DT) 1976-06-29 US disclosed
US-3957749-A WATER-INSOLUBLE MONOAZO PYRIDINE DYES CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative KRT18, NDUFB5, NDUFB7 KDM4E 440/4885USP2 3861/4885LMNA 459/4885
US-20070079452-A1 Agent and method for the oxidative coloring of keratin fibers KRT18, KIT, CKMT1A; CKMT1B KDM4E 1324/4885USP2 2810/4885LMNA 103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.