Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.37 |
| ▸ | CSF1R | P07333 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | WNT1 | P04628 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | CLK3 | P49761 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5681364 | 0.86 | KDM4E (0.39) | KDM4EALDH1A1HPGDLMNAHSD17B10 | |
| SCHEMBL5681111 | 0.84 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDLMNAHSD17B10 | |
| SCHEMBL5680865 | 0.82 | KDM4E (0.47) | KDM4EALDH1A1HPGDLMNAHSD17B10 | |
| SCHEMBL5680002 | 0.79 | KDM4E (0.53) | KDM4EALDH1A1HPGDLMNAHSD17B10 | |
| SCHEMBL11275888 | 0.74 | PIK3CG (0.41) | KDM4EALDH1A1HPGDLMNAHSD17B10 | |
| SCHEMBL5683277 | 0.71 | KDM4E (0.48) | KDM4EALDH1A1HPGDLMNAHSD17B10 | |
| SCHEMBL6664437 | 0.70 | KDM4E (0.46) | KDM4EALDH1A1HPGDLMNAHSD17B10 | |
| SCHEMBL6665312 | 0.68 | KDM4E (0.47) | KDM4EALDH1A1HPGDLMNAHSD17B10 | |
| SCHEMBL9805938 | 0.68 | KDM4E (0.50) | KDM4EALDH1A1HPGDLMNAHSD17B10 | |
| SCHEMBL5681929 | 0.67 | KDM4E (0.68) | KDM4EALDH1A1HPGDLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831869-A4 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | ELIZANOR BIOPHARMACEUTICALS IN (US) | 1999-04-21 | — | — | EP | disclosed |
| EP-0831869-A1 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | Elizanor Biopharmaceuticals, Inc. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040190-A1 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | ELIZANOR BIOPHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |