Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NEK2 | P51955 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PNP | P00491 | 1/20 | 0.36 |
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 2/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | LYN | P07948 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28141583 | 0.82 | XDH (0.41) | NEK2DPP4ALDH1A1XDHCDK2 | |
| SCHEMBL6551675 | 0.81 | DPP4 (0.56) | NEK2DPP4ALDH1A1PNPGDA | |
| SCHEMBL28387743 | 0.81 | PDPK1 (0.54) | NEK2DPP4ALDH1A1PNPGDA | |
| SCHEMBL8369704 | 0.75 | MEN1 (0.32) | — | |
| Acetic Acid SCHEMBL7594624 | 0.74 | DPP4 (0.48) | NEK2DPP4GDAXDHCDK2 | |
| SCHEMBL533603 | 0.71 | PDPK1 (0.44) | DPP4ALDH1A1PNPGDAPDPK1 | |
| SCHEMBL27337868 | 0.70 | CDK2 (0.54) | NEK2ALDH1A1CDK2HSD17B10CDK1 | |
| SCHEMBL355362 | 0.68 | PDPK1 (0.66) | DPP4GDAPDPK1PRKACACDK2 | |
| SCHEMBL1901598 | 0.68 | GDA (0.60) | PNPGDAXDHPOLA1 | |
| Lithium SCHEMBL30870625 | 0.67 | GDA (0.58) | PNPGDAXDHPOLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543095-B1 | Method for producing 2-amino-6-halogenopurine and synthesis of an intermediate therefore | SUMIKA FINE CHEMICALS CO LTD (JP) | 1999-01-20 | — | — | EP | disclosed |
| US-5440037-A | Method for production of 2-amino-6-halogenopurine derivatives | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5391733-A | Synthesis intermediates for 2-amino-6-halogenopurines | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5389637-A | 2-formylamino-6-halogenopurine | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0543095-A2 | Method for producing 2-amino-6-halogenopurine and synthesis intermediate therefor | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1993-05-26 | — | — | EP | disclosed |