Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.56 |
| ▸ | POLA1 | P09884 | 3/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | NEK2 | P51955 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PNP | P00491 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7594624 | 0.92 | DPP4 (0.48) | DPP4POLA1XDHNEK2GDA | |
| SCHEMBL28141583 | 0.82 | XDH (0.41) | DPP4XDHNEK2ALDH1A1ADORA3 | |
| SCHEMBL8369705 | 0.81 | NEK2 (0.37) | DPP4POLA1XDHNEK2ALDH1A1 | |
| SCHEMBL28387743 | 0.81 | PDPK1 (0.54) | DPP4POLA1XDHNEK2ALDH1A1 | |
| SCHEMBL27824249 | 0.78 | DPP4 (0.61) | DPP4POLA1XDHPNPPDPK1 | |
| SCHEMBL6551670 | 0.75 | DPP4 (0.31) | DPP4 | |
| SCHEMBL5197101 | 0.75 | GDA (0.54) | DPP4POLA1XDHNEK2GDA | |
| SCHEMBL8588220 | 0.74 | DPP4 (0.47) | DPP4POLA1XDHALDH1A1ADORA3 | |
| SCHEMBL9412467 | 0.73 | DPP4 (0.50) | DPP4POLA1XDHNEK2GDA | |
| SCHEMBL9412610 | 0.73 | DPP4 (0.50) | DPP4POLA1XDHNEK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6452004-B1 | USEFUL AS AN INTERMEDIATE OF A CARBOCYCLIC NUCLEOSIDE USEFULLY USED AS AN ANTI-VIRAL AGENT | KURARAY CO., LTD. (JP) | 2002-09-17 | — | — | US | claimed |
| EP-0773220-B1 | 2-Amino-6-chloropurine and method for preparing the same | SUMIKA FINE CHEMICALS CO LTD (JP) | 2002-02-13 | — | — | EP | claimed |
| EP-0861841-B1 | PROCESS FOR PRODUCING 2-AMINO-6-IODOPURINE | SUMIKA FINE CHEMICALS COMPANY (JP) | 2001-04-04 | — | — | EP | claimed |
| US-6127539-A | Cyclopentenecarboxamide derivative, method for preparing the same and bicycloamide derivative used therein | KURARAY CO., LTD. (JP) | 2000-10-03 | — | — | US | claimed |
| US-5994541-A | Process for producing 2-amino-6-iodopurine | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1999-11-30 | — | — | US | claimed |
| US-5817812-A | Cyclopentenecarboxamide derivative, method for preparing the same and bicycloamide derivative used therein | KURARAY CO., LTD. (JP) | 1998-10-06 | — | — | US | claimed |
| EP-0861841-A1 | PROCESS FOR PRODUCING 2-AMINO-6-IODOPURINE | SUMIKA FINE CHEMICALS Company, Limited (JP) | 1998-09-02 | — | — | EP | claimed |
| US-5789590-A | Double cone-like crystal form of 2-amino-6-chloropurine and preparation | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1998-08-04 | — | — | US | claimed |
| EP-0773220-A1 | 2-Amino-6-chloropurine and method for preparing the same | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1997-05-14 | — | — | EP | claimed |
| JP-10077284-A | — | — | None | — | — | JP | disclosed |
| JP-9188681-A | — | — | None | — | — | JP | disclosed |
| CN-117466895-A | Preparation method of 2-amino-6-chloropurine | 江苏八巨药业有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-113234077-B | Synthesis method of 2-amino-6-chloropurine | 上海凌凯医药科技有限公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-111592542-A | Method for synthesizing 2-amino-6-chloropurine | 上海凌凯医药科技有限公司 | 2020-08-28 | — | — | CN | disclosed |
| EP-0775705-A2 | Cyclopentenecarboxamide derivative, method for preparing the same and bicycloamide derivative used therein | KURARAY CO., LTD. (JP) | 1997-05-28 | — | — | EP | disclosed |
| EP-0773220-A1 | 2-Amino-6-chloropurine and method for preparing the same | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1997-05-14 | — | — | EP | disclosed |
| US-5440037-A | Method for production of 2-amino-6-halogenopurine derivatives | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5391733-A | Synthesis intermediates for 2-amino-6-halogenopurines | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5389637-A | 2-formylamino-6-halogenopurine | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0543095-A2 | Method for producing 2-amino-6-halogenopurine and synthesis intermediate therefor | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1993-05-26 | — | — | EP | disclosed |