SCHEMBL8370389

SCHEMBL8370389

O=C1C=CC(C(=O)O)c2cc3ccccc3cc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.38
CASP6 P55212 1/20 0.38
NQO1 P15559 1/20 0.37
EDNRB P24530 4/20 0.33
EDNRA P25101 4/20 0.33
HSP90AA1 P07900 1/20 0.33
PAX8 Q06710 1/20 0.33
IDO1 P14902 2/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
CDC25B P30305 1/20 0.32
AKT1 P31749 1/20 0.32
SNCA P37840 1/20 0.32
MAP2K1 Q02750 1/20 0.32
PIN1 Q13526 1/20 0.32
EHMT2 Q96KQ7 1/20 0.32
NSD1 Q96L73 1/20 0.32
EHMT1 Q9H9B1 1/20 0.32
PPIA P62937 1/20 0.31
CES2 O00748 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10601750 0.80 EDNRA (0.44) POLBEDNRBEDNRAIDO1MAOA
SCHEMBL29534567 0.68 CDC25B (0.60) POLBNQO1HSP90AA1IDO1MAOA
SCHEMBL449382 0.68 CDC25B (0.60) POLBNQO1HSP90AA1IDO1MAOA
SCHEMBL29401941 0.66 EDNRA (0.39) EDNRBEDNRAMEN1ALDH1A1KMT2A
SCHEMBL63928 0.66 EDNRA (0.39) EDNRBEDNRAMEN1ALDH1A1KMT2A
SCHEMBL8917182 0.66 EDNRA (0.46) EDNRBEDNRACES2CES1MEN1
Ammonia Solution, Strong SCHEMBL28326620 0.66 CDC25B (0.57) POLBNQO1HSP90AA1IDO1MAOA
SCHEMBL7036459 0.66 POLB (0.46) POLBCASP6EDNRBEDNRAHSP90AA1
SCHEMBL32690147 0.65 ALDH1A1 (0.40) POLBCASP6EDNRBEDNRAKDM4E
SCHEMBL28970647 0.65 EDNRA (0.38) EDNRBEDNRAMEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0760378-B1 Polymer scale deposition preventive agent SHINETSU CHEMICAL CO (JP) 1999-01-27 EP disclosed
US-5728781-A POLYMERIZING AN UNSATURATED MONOMER IN A VESSEL HAVING A COATING FILM ON THE INNER WALL SURFACE THEREOF SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-03-17 US disclosed
EP-0760378-A1 Polymer scale deposition preventive agent SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-03-05 EP disclosed