SCHEMBL8370543

SCHEMBL8370543

CO[Si](C)(OC)C(C)C(C)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.33
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28447376 0.77 TP53 (0.38) TP53
SCHEMBL8370492 0.70 TP53 (0.36) TP53
SCHEMBL5416178 0.68
SCHEMBL812166 0.66 TP53 (0.57) TP53ALDH1A1
SCHEMBL83830 0.66 TP53 (0.57) TP53ALDH1A1
SCHEMBL13310465 0.66 TP53 (0.57) TP53ALDH1A1
SCHEMBL715386 0.66 TP53 (0.57) TP53ALDH1A1
SCHEMBL812149 0.66 TP53 (0.57) TP53ALDH1A1
SCHEMBL28447355 0.65 TP53 (0.36) TP53
SCHEMBL5462613 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0421644-B1 Method for preparation of organoalkoxysilanes DOW CORNING (US) 1999-01-20 EP disclosed
EP-0421644-A2 Method for preparation of organoalkoxysilanes DOW CORNING CORPORATION (US) 1991-04-10 EP disclosed
US-4924022-A Method for preparation of organoalkoxysilanes DOW CORNING CORPORATION (US) 1990-05-08 US disclosed