Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812166 | 1.00 | TP53 (0.57) | TP53SLC7A5TSHRLMNAALDH1A1 | |
| SCHEMBL715386 | 1.00 | TP53 (0.57) | TP53SLC7A5TSHRLMNAALDH1A1 | |
| SCHEMBL83830 | 1.00 | TP53 (0.57) | TP53SLC7A5TSHRLMNAALDH1A1 | |
| SCHEMBL13310465 | 1.00 | TP53 (0.57) | TP53SLC7A5TSHRLMNAALDH1A1 | |
| SCHEMBL6735445 | 0.96 | TP53 (0.53) | TP53SLC7A5TSHRLMNAALDH1A1 | |
| SCHEMBL11445671 | 0.96 | TP53 (0.53) | TP53SLC7A5TSHRLMNAALDH1A1 | |
| SCHEMBL11445718 | 0.96 | TP53 (0.53) | TP53SLC7A5TSHRLMNAALDH1A1 | |
| SCHEMBL9635648 | 0.89 | TP53 (0.47) | TP53SLC7A5TSHRLMNAALDH1A1 | |
| SCHEMBL25575130 | 0.86 | TP53 (0.44) | TP53SLC7A5TSHRALDH1A1FFAR3 | |
| SCHEMBL10570748 | 0.86 | TP53 (0.44) | TP53SLC7A5TSHRALDH1A1FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198463-B2 | Process for the preparation of 6,6-dimethyl-3-azabicyclo-[3.3.0]-hexane compounds and enantiomeric salts thereof | SCHERING CORPORATION (US) | 2012-06-12 | — | — | US | disclosed |
| US-7906676-B2 | Process for preparing 3-amino-5-fluoro-4-dialkoxypentanoic acid ester | LG LIFE SCIENCES LTD. (KR) | 2011-03-15 | — | — | US | disclosed |
| US-20100256393-A1 | PROCESS FOR THE PREPARATION OF 6,6- DIMETHYL-3-AZABICYCLO-[3.1.0]-HEXANE COMPOUNDS AND ENANTIOMERIC SALTS THEREOF | SCHERING CORPORATION (US) | 2010-10-07 | — | — | US | disclosed |
| US-7723531-B2 | Process for the preparation of 6,6-dimethyl-3-azabicyclo-[3.1.0]-hexane compounds and enantiomeric salts thereof | SCHERING CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |
| US-20100036158-A1 | NOVEL PROCESS FOR PREPARING 3-AMINO-5-FLUORO-4-DIALKOXYPENTANOIC ACID ESTER | LG LIFE SCIENCES LTD. (KR) | 2010-02-11 | — | — | US | disclosed |
| US-20090240063-A1 | Process For The Preparation Of 6,6-Dimethyl-3-Azabicyclo-[3.1.0]-Hexane Compounds ... | MERCK SHARP & DOHME CORP. | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256393-A1 | PROCESS FOR THE PREPARATION OF 6,6- DIMETHYL-3-AZABICYCLO-[3.1.0]-HEXANE COMPOUNDS AND ENANTIOMERIC SALTS THEREOF | TMT1A, HDHD5, DLST | TP53 2984/4885SLC7A5 280/4885TSHR 2000/4885 |
| US-20100036158-A1 | NOVEL PROCESS FOR PREPARING 3-AMINO-5-FLUORO-4-DIALKOXYPENTANOIC ACID ESTER | DAO, AASDHPPT, ALAD | TP53 4308/4885SLC7A5 345/4885TSHR 2522/4885 |
| US-20090240063-A1 | Process For The Preparation Of 6,6-Dimethyl-3-Azabicyclo-[3.1.0]-Hexane Compounds ... | TMT1A, HDHD5, TET1 | TP53 2998/4885SLC7A5 559/4885TSHR 1970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.