Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8370567 | 1.00 | HTT (0.58) | HTTPOLBAPEX1TDP1NPC1 | |
| SCHEMBL9551567 | 0.85 | MMP14 (0.41) | HTTPOLBAPEX1TDP1NPC1 | |
| SCHEMBL9551568 | 0.85 | MMP14 (0.41) | HTTPOLBAPEX1TDP1NPC1 | |
| SCHEMBL9317012 | 0.84 | MMP14 (0.41) | HTTPOLBAPEX1TDP1NPC1 | |
| SCHEMBL9317009 | 0.84 | MMP14 (0.41) | HTTPOLBAPEX1TDP1NPC1 | |
| SCHEMBL9551060 | 0.84 | MMP14 (0.61) | HTTPOLBAPEX1TDP1NPC1 | |
| SCHEMBL9436600 | 0.84 | MMP14 (0.61) | HTTPOLBAPEX1TDP1NPC1 | |
| SCHEMBL8748245 | 0.84 | MMP14 (0.61) | HTTPOLBAPEX1TDP1NPC1 | |
| SCHEMBL28456770 | 0.82 | HTT (0.85) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL8365990 | 0.82 | TDP1 (0.52) | HTTPOLBAPEX1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11322690-A | — | — | None | — | — | JP | disclosed |
| JP-H11322690-A | NEW DIVINYL COMPOUND AND ITS PRODUCTION | AGENCY OF IND SCIENCE & TECHNOL | 1999-11-24 | — | — | JP | disclosed |