SCHEMBL9317009

SCHEMBL9317009

C=C(C)C(=O)OCCCCCCN(C)c1ccc(/N=N/c2ccc(S(=O)(=O)c3ccccc3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP14 P50281 1/20 0.41
POLB P06746 3/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
TSHR P16473 2/20 0.37
CA12 O43570 3/20 0.36
CA2 P00918 3/20 0.36
CA9 Q16790 3/20 0.36
F2 P00734 3/20 0.34
PRSS1 P07477 2/20 0.34
PRSS2 P07478 2/20 0.34
PRSS3 P35030 2/20 0.34
MAPK1 P28482 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
PSEN1 P49768 1/20 0.33
PSEN2 P49810 1/20 0.33
APH1B Q8WW43 1/20 0.33
NCSTN Q92542 1/20 0.33
APH1A Q96BI3 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9317012 1.00 MMP14 (0.41) MMP14POLBAPEX1HTTTDP1
SCHEMBL9317136 0.92 MMP14 (0.39) MMP14POLBAPEX1HTTTDP1
SCHEMBL9317141 0.92 MMP14 (0.39) MMP14POLBAPEX1HTTTDP1
SCHEMBL9551567 0.89 MMP14 (0.41) MMP14POLBAPEX1HTTTDP1
SCHEMBL9551568 0.89 MMP14 (0.41) MMP14POLBAPEX1HTTTDP1
SCHEMBL9317170 0.88 POLB (0.40) POLBAPEX1HTTTDP1TSHR
SCHEMBL9317175 0.88 POLB (0.40) POLBAPEX1HTTTDP1TSHR
SCHEMBL9317085 0.86 MMP14 (0.41) MMP14POLBTSHRCA12CA2
SCHEMBL9317088 0.86 MMP14 (0.41) MMP14POLBTSHRCA12CA2
SCHEMBL8370567 0.84 HTT (0.58) MMP14POLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5322986-A Methods for preparing polymer stripe waveguides and polymer stripe waveguides prepared thereby EASTMAN KODAK COMPANY (US) 1994-06-21 US disclosed
US-5157541-A Support with dielectric, reflection metal, polymeric electrooptical layers, couterelectrode EASTMAN KODAK COMPANY (US) 1992-10-20 US disclosed
US-5075796-A OPTICAL ARTICLE FOR MULTICOLOR IMAGING EASTMAN KODAK COMPANY (US) 1991-12-24 US disclosed
US-4948225-A REFLECTIVE METAL LAYER, DIELECTRICS, PROTECTIVE COATING EASTMAN KODAK COMPANY (US) 1990-08-14 US disclosed