SCHEMBL8370615

SCHEMBL8370615

CNC(=O)C(=NOC)c1ccccc1Oc1cccc(OC2CCCCO2)c1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.35
HSD11B1 P28845 1/20 0.35
KAT2B Q92831 1/20 0.35
BAZ2B Q9UIF8 1/20 0.35
HIF1A Q16665 4/20 0.34
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34
TSHR P16473 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
SLC6A3 Q01959 2/20 0.33
RAB9A P51151 1/20 0.32
MTNR1B P49286 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
PKM P14618 1/20 0.32
KDM4E B2RXH2 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8954773 1.00 DHFR (0.35) DHFRHSD11B1KAT2BBAZ2BHIF1A
SCHEMBL8370504 0.80 RAB9A (0.44) HIF1AGAATSHRRAB9AMTNR1B
SCHEMBL8370505 0.80 RAB9A (0.44) HIF1AGAATSHRRAB9AMTNR1B
SCHEMBL8368474 0.80 POLB (0.50) HIF1ARAB9AMTNR1BMEN1KMT2A
SCHEMBL8954792 0.80 RAB9A (0.44) HIF1AGAATSHRRAB9AMTNR1B
SCHEMBL8368475 0.80 POLB (0.50) HIF1ARAB9AMTNR1BMEN1KMT2A
SCHEMBL6654536 0.80 TDP1 (0.39) KAT2BBAZ2BALDH1A1TDP1SLC6A3
SCHEMBL8371669 0.79 KDM4E (0.49) HIF1ARAB9AMTNR1BMEN1KMT2A
SCHEMBL8371670 0.79 KDM4E (0.49) HIF1ARAB9AMTNR1BMEN1KMT2A
SCHEMBL8954923 0.79 KDM4E (0.49) HIF1ARAB9AMTNR1BMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0617011-B1 Process for producing alkoxyiminoacetamide compounds SHIONOGI & CO (JP) 1999-01-20 EP disclosed
EP-0398692-B1 Alkoxyiminoacetamide derivatives and their use as fungicides SHIONOGI & CO (JP) 1996-08-21 EP disclosed
US-5548078-A FOR AGRICULTURE SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1996-08-20 US disclosed
US-5506358-A USEFUL AS AGRICULTURAL FUNGICIDES SHIONOGI & CO., LTD. (JP) 1996-04-09 US disclosed
EP-0629609-A1 Process for the preparation of Alkoxyiminoacetamide derivatives and an intermediate therefor SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1994-12-21 EP disclosed
US-5371223-A Controlling phytopathogens SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1994-12-06 US disclosed
US-5371222-A Intermediates SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1994-12-06 US disclosed
EP-0617011-A2 Process for producing alkoxyiminoacetamide compounds SHIONOGI & CO., LTD. (JP) 1994-09-28 EP disclosed
US-5185342-A ALKOXYIMINOACETAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1993-02-09 US disclosed
EP-0398692-A2 Alkoxyiminoacetamide derivatives and their use as fungicides SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1990-11-22 EP disclosed