Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 2/20 | 0.52 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | KLK1 | P06870 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 7/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.43 |
| ▸ | F12 | P00748 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31098952 | 0.84 | EGFR (0.57) | EGFRAPPGRM4WNT3AUTS2R | |
| SCHEMBL6477749 | 0.84 | EGFR (0.57) | EGFRAPPGRM4WNT3AUTS2R | |
| Methane SCHEMBL9378754 | 0.82 | EGFR (0.55) | EGFRAPPGRM4WNT3AUTS2R | |
| SCHEMBL10055014 | 0.82 | WNT3A (0.54) | EGFRAPPGRM4WNT3AUTS2R | |
| SCHEMBL27990386 | 0.78 | EGFR (0.71) | AURKARPS6KB1ELANEEGFRAPP | |
| SCHEMBL9927462 | 0.77 | CYP1A2 (0.56) | EGFR | |
| SCHEMBL7127641 | 0.77 | AHR (0.58) | EGFRF12PLAUNCF1NOS3 | |
| SCHEMBL10055013 | 0.75 | WNT3A (0.48) | EGFRGRM4WNT3AUTS2R | |
| SCHEMBL7122983 | 0.73 | AURKA (0.43) | AURKARPS6KB1GRM4 | |
| SCHEMBL509566 | 0.72 | EGFR (0.64) | AURKARPS6KB1EGFRIGF1RAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11130750-A | — | — | None | — | — | JP | disclosed |
| JP-H11130750-A | NOVEL DERIVATIVE | FUJISAWA PHARMACEUT CO LTD | 1999-05-18 | — | — | JP | disclosed |