Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9189826 | 0.84 | MEN1 (0.51) | EPHX1KCNA5MEN1GAAKMT2A | |
| SCHEMBL2499196 | 0.79 | ANPEP (0.33) | GAAALDH1A1 | |
| SCHEMBL5949707 | 0.77 | EPHX1 (0.48) | EPHX1KCNA5GAA | |
| SCHEMBL963928 | 0.74 | — | — | |
| SCHEMBL28370348 | 0.73 | C3AR1 (0.34) | EPHX1MEN1GAAKMT2A | |
| SCHEMBL28937234 | 0.73 | HTR2A (0.31) | — | |
| SCHEMBL7765762 | 0.72 | GABRR1 (0.50) | EPHX1KCNA5CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL20616625 | 0.72 | EPHX1 (0.48) | EPHX1KCNA5CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL28231142 | 0.72 | EPHX1 (0.44) | EPHX1KCNA5CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL8372587 | 0.72 | EPHX1 (0.33) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649850-B1 | Process for making isocyanatoorganosilanes | OSI SPECIALTIES INC (US) | 1999-01-27 | — | — | EP | disclosed |
| EP-0649850-A1 | Process for making isocyanatoorganosilanes | OSi Specialties, Inc. (US) | 1995-04-26 | — | — | EP | disclosed |
| US-5393910-A | Process for making isocyanatoorganosilanes | OSI SPECIALTIES, INC. (US) | 1995-02-28 | — | — | US | disclosed |