SCHEMBL2499196

SCHEMBL2499196

C=C(C)C(=O)NCCC(C)[SiH](OC)OC

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 3/20 0.33
RNPEP Q9H4A4 3/20 0.33
DNPEP Q9ULA0 2/20 0.33
ALDH1A1 P00352 1/20 0.32
TGFBR1 P36897 1/20 0.32
SMN1; SMN2 Q16637 3/20 0.31
RAB9A P51151 2/20 0.31
GAA P10253 1/20 0.31
TSHR P16473 1/20 0.31
NPC1 O15118 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8370787 0.79 EPHX1 (0.41) ALDH1A1GAA
SCHEMBL553719 0.77 ALDH1A1 (0.35) ANPEPRNPEPDNPEPALDH1A1TGFBR1
SCHEMBL23269488 0.77 ALDH1A1 (0.35) ANPEPRNPEPDNPEPALDH1A1TGFBR1
SCHEMBL3235398 0.76 ANPEP (0.52) ANPEPRNPEPDNPEPTGFBR1SMN1; SMN2
SCHEMBL3272669 0.75 ALDH1A1 (0.37) ANPEPRNPEPDNPEPALDH1A1TGFBR1
SCHEMBL157717 0.74 ALDH1A1 (0.45) ANPEPRNPEPDNPEPALDH1A1TGFBR1
SCHEMBL22557600 0.74 BBOX1 (0.41) ANPEPRNPEPDNPEPALDH1A1TGFBR1
SCHEMBL5722555 0.73 ANPEP (0.44) ANPEPRNPEPDNPEPALDH1A1TGFBR1
Bromide SCHEMBL6117256 0.72 BBOX1 (0.40) ANPEPRNPEPDNPEPTGFBR1SMN1; SMN2
Hydrochloric Acid SCHEMBL22557508 0.72 BBOX1 (0.40) ANPEPRNPEPDNPEPTGFBR1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2084217-A2 PROCESS FOR CROSSLINKING THERMOPLASTIC POLYMERS WITH SILANES EMPLOYING PEROXIDE BLENDS, THE RESULTING CROSSLINKED THERMOPLASTIC POLYMER COMPOSITION AND ARTICLES MADE THEREFROM Momentive Performance Materials Inc. (US) 2009-08-05 EP claimed
WO-2008060508-A2 PROCESS FOR CROSSLINKING THERMOPLASTIC POLYMERS WITH SILANES EMPLOYING PEROXIDE BLENDS, THE RESULTING CROSSLINKED THERMOPLASTIC POLYMER COMPOSITION AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-05-22 WO claimed
US-20080114134-A1 Process for crosslinking thermoplastic polymers with silanes employing peroxide blends, the resulting crosslinked thermoplastic polymer composition and articles made therefrom GENERAL ELECTRIC COMPANY (US) 2008-05-15 US claimed
US-8030415-B2 Process for crosslinking thermoplastic polymers with silanes employing peroxide blends, the resulting crosslinked thermoplastic polymer composition and articles made therefrom MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2011-10-04 US disclosed
US-20100204409-A1 Process For Crosslinking Thermoplastic Polymers With Silanes Employing Peroxide Blends, The Resulting Crosslinked Thermoplastic Polymer Composition And Articles Made Therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-08-12 US disclosed
EP-2084217-A2 PROCESS FOR CROSSLINKING THERMOPLASTIC POLYMERS WITH SILANES EMPLOYING PEROXIDE BLENDS, THE RESULTING CROSSLINKED THERMOPLASTIC POLYMER COMPOSITION AND ARTICLES MADE THEREFROM Momentive Performance Materials Inc. (US) 2009-08-05 EP disclosed
WO-2008060508-A2 PROCESS FOR CROSSLINKING THERMOPLASTIC POLYMERS WITH SILANES EMPLOYING PEROXIDE BLENDS, THE RESULTING CROSSLINKED THERMOPLASTIC POLYMER COMPOSITION AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-05-22 WO disclosed
US-20080114134-A1 Process for crosslinking thermoplastic polymers with silanes employing peroxide blends, the resulting crosslinked thermoplastic polymer composition and articles made therefrom GENERAL ELECTRIC COMPANY (US) 2008-05-15 US disclosed