SCHEMBL8370815

SCHEMBL8370815

O=[N+]([O-])c1cc[c]c2[c]cccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.52
ALDH1A1 P00352 6/20 0.46
CTSB P07858 4/20 0.43
POLB P06746 1/20 0.40
CYP3A4 P08684 1/20 0.40
ALOX15 P16050 1/20 0.40
HSD17B10 Q99714 1/20 0.40
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
TSHR P16473 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
CASP6 P55212 2/20 0.37
NCOA1 Q15788 1/20 0.37
NCOA3 Q9Y6Q9 1/20 0.37
GAA P10253 1/20 0.37
KDM4E B2RXH2 1/20 0.37
NPC1 O15118 1/20 0.37
BRD4 O60885 1/20 0.37
LMNA P02545 1/20 0.37
HSP90AA1 P07900 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8584895 0.78 TDP1 (0.40) TDP1ALDH1A1CTSBPOLBCYP3A4
SCHEMBL249714 0.77 TDP1 (0.52) TDP1ALDH1A1CTSBPOLBCYP3A4
SCHEMBL4306587 0.76 TDP1 (0.61) TDP1ALDH1A1CTSBPOLBCYP3A4
SCHEMBL386455 0.76 TDP1 (0.61) TDP1ALDH1A1CTSBPOLBCYP3A4
SCHEMBL4303054 0.73 TDP1 (0.42) TDP1ALDH1A1CTSBCYP3A4ALOX15
SCHEMBL2123769 0.72 POLB (0.54) TDP1ALDH1A1CTSBPOLBMEN1
SCHEMBL33832 0.69 TDP1 (0.46) TDP1ALDH1A1HSD17B10MEN1KMT2A
SCHEMBL7136437 0.69 TDP1 (0.46) TDP1ALDH1A1HSD17B10MEN1KMT2A
SCHEMBL7788656 0.69 TDP1 (0.80) TDP1ALDH1A1CTSBPOLBCYP3A4
SCHEMBL29475175 0.69 TDP1 (1.00) TDP1ALDH1A1CTSBPOLBCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0750230-B1 Negative type photosensitive compositions FUJI PHOTO FILM CO LTD (JP) 1999-02-10 EP disclosed
US-5725994-A CONTAINING AN ACID PRECURSOR AND A HYDROXYL GROUP CONTAINING LINEAR POLYMER FUJI PHOTO FILM CO., LTD. (JP) 1998-03-10 US disclosed
EP-0750230-A2 Negative type photosensitive compositions FUJI PHOTO FILM CO., LTD. (JP) 1996-12-27 EP disclosed
US-4399210-A O-NAPHTHOQUINONEDIAZIDE AND A DISCOLORING AGENT FUJI PHOTO FILM COMPANY LTD. (JP) 1983-08-16 US disclosed