SCHEMBL33832

SCHEMBL33832

O=[N+]([O-])c1[c]cccc1[N+](=O)[O-]

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.46
KMT2A Q03164 2/20 0.45
MEN1 O00255 1/20 0.45
GPR35 Q9HC97 2/20 0.45
HSD17B10 Q99714 1/20 0.43
ALDH1A1 P00352 8/20 0.41
TSHR P16473 3/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
S100A4 P26447 1/20 0.39
NPC1 O15118 1/20 0.38
RECQL P46063 1/20 0.38
RAB9A P51151 1/20 0.38
MAPK1 P28482 1/20 0.37
CASP7 P55210 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7136437 1.00 TDP1 (0.46) TDP1KMT2AMEN1GPR35HSD17B10
SCHEMBL6195273 0.83 ALDH1A1 (0.52) TDP1KMT2AMEN1GPR35HSD17B10
SCHEMBL7747225 0.79 GPR35 (0.46) TDP1KMT2AMEN1GPR35HSD17B10
SCHEMBL1179579 0.77 PDE7A (0.35) TDP1KMT2AMEN1GPR35ALDH1A1
SCHEMBL7907932 0.77 TDP1 (0.45) TDP1KMT2AMEN1GPR35HSD17B10
SCHEMBL8374 0.77 TDP1 (0.54) TDP1KMT2AMEN1GPR35HSD17B10
SCHEMBL2075134 0.77 TDP1 (0.45) TDP1KMT2AMEN1GPR35HSD17B10
SCHEMBL2193445 0.77 LMNA (0.33) TDP1KMT2AMEN1GPR35ALDH1A1
SCHEMBL2075135 0.77 MAPT (0.36) TDP1KMT2AMEN1GPR35HSD17B10
SCHEMBL455622 0.77 ALDH1A1 (0.48) TDP1HSD17B10ALDH1A1TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 16344 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111201328-B Detection of recombinant enzyme polymerase amplification using double hapten probes 雅培诊断产品士嘉堡公司 2024-07-02 CN claimed
WO-2024135454-A1 COMPOSITE PARTICLES, BINDER COMPOSITION FOR NONAQUEOUS SECONDARY BATTERIES AND NONAQUEOUS SECONDARY BATTERY ELECTRODE 株式会社レゾナック 2024-06-27 WO claimed
WO-2024135437-A1 BINDER COMPOSITION FOR NONAQUEOUS SECONDARY BATTERIES AND NONAQUEOUS SECONDARY BATTERY ELECTRODE 株式会社レゾナック 2024-06-27 WO claimed
US-20240197898-A1 SUBSTITUTED BENZO[5,6][1,4]DIAZEPINO[1,2-a]INDOLES FOR THE TREATMENT OF PROLIFERATIVE DISORDERS IMMUNOGEN, INC. 2024-06-20 US claimed
WO-2024123835-A1 ENGINEERED SWITCHES FOR IMMUNE CELL ACTIVITY AND METHODS OF USE THEREOF DYNAMIC CELL THERAPIES, INC. (US) 2024-06-13 WO claimed
WO-2024123836-A1 IMMUNE-ACTIVATING COMPLEXES DYNAMIC CELL THERAPIES, INC. (US) 2024-06-13 WO claimed
WO-2024102956-A1 KETO-AMIDE-BASED FIBROBLAST ACTIVATION PROTEIN-TARGETED LIGAND LINKED TO AN IMAGING OR THERAPEUTIC AGENT, COMPOSITIONS AND METHODS OF USE PURDUE RESEARCH FOUNDATION (US) 2024-05-16 WO claimed
CN-118020177-A Negative electrode for secondary battery and secondary battery 株式会社村田制作所 2024-05-10 CN claimed
EP-3507603-B1 COMPOSITIONS AND METHODS FOR ENHANCED FLUORESCENCE LIFE TECHNOLOGIES CORP (US) 2024-03-06 EP claimed
US-11920172-B2 Reprogramming urokinase into an antibody-recruiting anticancer agent YALE UNIVERSITY (US) 2024-03-05 US claimed
US-3996052-A Phototropic compounds as acid catalyst in photopolymerizing process AMERICAN CAN COMPANY (US) 1976-12-07 US claimed
US-3992377-A 3-Thio-substituted cephalosporin antibiotics ELI LILLY AND COMPANY (US) 1976-11-16 US claimed
US-3991202-A ANTIMICROBIALS JANSSEN PHARMACEUTICA N.V. (BE) 1976-11-09 US claimed
US-3963695-A Tetradeoxyneamine and derivatives thereof SMITHKLINE CORPORATION (US) 1976-06-15 US claimed
US-3960838-A Mercaptopseudodisaccharides SMITHKLINE CORPORATION (US) 1976-06-01 US claimed
US-3959078-A Enzyme immobilization with a thermochemical-photochemical bifunctional agent MIDWEST RESEARCH INSTITUTE (US) 1976-05-25 US claimed
US-3957779-A ANTIMICROBIAL AGENTS BAYER AKTIENGESELLSCHAFT (DT) 1976-05-18 US claimed
US-3953416-A Synthetic decapeptide having the activity of the luteinizing hormone releasing hormone and method for manufacturing the same FOLKERS KARL 1976-04-27 US claimed
US-3949143-A Epoxy resin coatings cured with phototropic aromatic nitro compounds AMERICAN CAN COMPANY (US) 1976-04-06 US claimed
US-3944545-A Process for preparing desacetoxycephalosporins ELI LILLY AND COMPANY (US) 1976-03-16 US claimed