Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 9/20 | 0.47 |
| ▸ | THRA | P10827 | 7/20 | 0.47 |
| ▸ | PPARG | P37231 | 6/20 | 0.47 |
| ▸ | RXRA | P19793 | 3/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 2/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8370895 | 1.00 | THRB (0.47) | THRBTHRAPPARGRXRAITGB3 | |
| SCHEMBL8369344 | 0.94 | THRB (0.44) | THRBTHRAPPARGRXRAITGB3 | |
| SCHEMBL8369345 | 0.94 | THRB (0.44) | THRBTHRAPPARGRXRAITGB3 | |
| SCHEMBL8371977 | 0.92 | THRB (0.56) | THRBTHRAPPARGRXRAITGB3 | |
| SCHEMBL8371976 | 0.92 | THRB (0.56) | THRBTHRAPPARGRXRAITGB3 | |
| SCHEMBL8370753 | 0.90 | THRB (0.43) | THRBTHRAPPARGRXRAITGB3 | |
| SCHEMBL8370758 | 0.90 | THRB (0.43) | THRBTHRAPPARGRXRAITGB3 | |
| Bromide SCHEMBL8371125 | 0.90 | THRB (0.42) | THRBTHRAPPARGRXRAITGB3 | |
| Bromide SCHEMBL8371119 | 0.90 | THRB (0.42) | THRBTHRAPPARGRXRAITGB3 | |
| SCHEMBL8370704 | 0.89 | YAP1 (0.43) | THRBTHRAPPARGRXRALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0576095-B1 | Immunoassays with labeled thyronine hapten analogues | JOHNSON & JOHNSON CLIN DIAG (US) | 1999-01-27 | — | — | EP | disclosed |
| US-5527709-A | Immunoassays with labeled thyronine hapten analogues | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1996-06-18 | — | — | US | disclosed |
| EP-0576095-A1 | Immunoassays with labeled thyronine hapten analogues | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1993-12-29 | — | — | EP | disclosed |