SCHEMBL837169

SCHEMBL837169

COC(C)(CO[SiH3])OC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31369016 0.73
SCHEMBL31369015 0.73
SCHEMBL432682 0.71
SCHEMBL11655700 0.71 ALDH1A1 (0.30)
SCHEMBL106926 0.69
SCHEMBL5701967 0.69
SCHEMBL5701714 0.69
SCHEMBL8088106 0.67
SCHEMBL10457839 0.67
SCHEMBL6250807 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113637173-B Modified sulfydryl-containing liquid silicone resin, nontoxic, colorless and odorless photocuring liquid silicone rubber, and preparation methods and applications thereof 深圳先进技术研究院 2022-12-20 CN claimed
CN-113637173-A Modified sulfydryl-containing liquid silicone resin, nontoxic, colorless and odorless photocuring liquid silicone rubber, and preparation method and application thereof 深圳先进技术研究院 2021-11-12 CN claimed
US-9546237-B2 Stabilization of polymers that contain a hydrolyzable functionality BRIDGESTONE CORPORATION (JP) 2017-01-17 US claimed
EP-3864059-B1 MODIFIED DIENE COPOLYMERS WITH TARGETED AND STABILIZED VISCOSITY FIRESTONE POLYMERS LLC (US) 2026-01-14 EP disclosed
US-20250179221-A1 HIGHLY FUNCTIONALIZED STABLE HYDROCARBYLOXYSILYL POLYDIENES AND POLYDIENE COPOLYMERS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2025-06-05 US disclosed
US-20250092168-A1 HIGHLY FUNCTIONALIZED STABLE DIHYDROCARBYLOXYSILYL POLYDIENES AND POLYDIENE COPOLYMERS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2025-03-20 US disclosed
EP-4460537-A1 HIGHLY FUNCTIONALIZED STABLE DIHYDROCARBYLOXYSILYL POLYDIENES AND POLYDIENE COPOLYMERS Bridgestone Americas Tire Operations, LLC (US) 2024-11-13 EP disclosed
WO-2023158819-A1 HIGHLY FUNCTIONALIZED STABLE HYDROCARBYLOXYSILYL POLYDIENES AND POLYDIENE COPOLYMERS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2023-08-24 WO disclosed
WO-2023133557-A1 HIGHLY FUNCTIONALIZED STABLE DIHYDROCARBYLOXYSILYL POLYDIENES AND POLYDIENE COPOLYMERS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2023-07-13 WO disclosed
CN-113637173-A Modified sulfydryl-containing liquid silicone resin, nontoxic, colorless and odorless photocuring liquid silicone rubber, and preparation method and application thereof 深圳先进技术研究院 2021-11-12 CN disclosed
US-20210340286-A1 Modified Diene Copolymers With Targeted And Stabilized Viscosity FIRESTONE POLYMERS, LLC (US) 2021-11-04 US disclosed
US-20050059835-A1 Methods of refining silane compounds HONEYWELL INTERNATIONAL INC. (US) 2005-03-17 US disclosed
US-20040188846-A1 Porous film, composition and manufacturing method, interlayer dielectric film, and semiconductor device PANASONIC CORPORATION (JP) 2004-09-30 US disclosed
EP-0586184-B1 Polydimethylsiloxanes for modulus reduction and method for their preparation DOW CORNING (US) 1997-10-01 EP disclosed
US-5357025-A Reaction product of hydrolyzable silane component and fluorocarbon alcohol cured with polysiloxane DOW CORNING CORPORATION (US) 1994-10-18 US disclosed
US-5340899-A Method for the preparation of polydimethylsiloxanes having low reactivity endgroups and high reactivity endgroups wherein the polydimethylsiloxanes contain ethylene chain linkages DOW CORNING CORPORATION (US) 1994-08-23 US disclosed
EP-0587295-A1 Sealant with siloxaphobic surface, composition and method to prepare same DOW CORNING CORPORATION (US) 1994-03-16 EP disclosed
EP-0586184-A2 Polydimethylsiloxanes for modulus reduction and method for their preparation DOW CORNING CORPORATION (US) 1994-03-09 EP disclosed
US-5264603-A Mixing a hydroxy endblocked polymer with hydrolyzable silane DOW CORNING CORPORATION (US) 1993-11-23 US disclosed
EP-0523242-A1 CURABLE RESIN COMPOSITION KANSAI PAINT CO. LTD. (JP) 1993-01-20 EP disclosed