SCHEMBL8371799

SCHEMBL8371799

CCOc1ccc2sn(-c3ccccc3)c(=O)c2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MPI P34949 10/20 0.58
PMM2 O15305 7/20 0.58
PHOSPHO1 Q8TCT1 7/20 0.58
APOBEC3G Q9HC16 5/20 0.58
TLR9 Q9NR96 3/20 0.58
G6PD P11413 9/20 0.55
MAPT P10636 3/20 0.55
KDM4E B2RXH2 2/20 0.55
ALDH1A1 P00352 2/20 0.55
PKM P14618 2/20 0.55
HPGD P15428 2/20 0.55
ALOX12 P18054 2/20 0.55
CASP3 P42574 2/20 0.55
NPSR1 Q6W5P4 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
HSP90AA1 P07900 1/20 0.55
MIF P14174 2/20 0.53
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
EP300 Q09472 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8372534 0.86 MPI (0.72) MPIPMM2PHOSPHO1APOBEC3GTLR9
SCHEMBL8371849 0.83 G6PD (0.74) MPIPMM2PHOSPHO1APOBEC3GG6PD
SCHEMBL8370661 0.77 MPI (0.68) MPIPMM2PHOSPHO1APOBEC3GTLR9
SCHEMBL8373532 0.74 MIF (0.74) MPIPMM2PHOSPHO1APOBEC3GTLR9
SCHEMBL1900805 0.74 MPI (1.00) MPIPMM2PHOSPHO1APOBEC3GTLR9
SCHEMBL8370679 0.74 G6PD (0.68) MPIPMM2PHOSPHO1APOBEC3GTLR9
SCHEMBL8369455 0.74 MIF (0.73) MPIPMM2PHOSPHO1APOBEC3GTLR9
SCHEMBL8371836 0.73 G6PD (0.70) MPIPMM2PHOSPHO1APOBEC3GG6PD
SCHEMBL1898397 0.72 MPI (1.00) MPIPMM2PHOSPHO1APOBEC3GTLR9
SCHEMBL8373518 0.72 MPI (0.57) MPIPMM2PHOSPHO1APOBEC3GG6PD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0644243-B1 Anti-fouling compositions or fouling control of harmful aquatic oranisms SUMITOMO CHEMICAL CO (JP) 1999-01-27 EP disclosed