SCHEMBL8372009

SCHEMBL8372009

CCC(O)NC(=O)OC(O)CC

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
CTSK P43235 3/20 0.35
ALOX15 P16050 1/20 0.32
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11848506 0.83 MGAM (0.36) TSHRCTSKALOX15MGAMGAA
SCHEMBL7369864 0.79
SCHEMBL28070032 0.77
SCHEMBL10439670 0.77 TSHR (0.46) TSHRMGAMGAASIMGAM2
SCHEMBL1348575 0.76 GAA (0.48) ALOX15MGAMGAASIMGAM2
SCHEMBL1115800 0.72 CTSK (0.50) CTSKGAA
SCHEMBL10717897 0.72 CHRNB2 (0.42) TSHRALOX15
SCHEMBL27618759 0.72 TSHR (0.37) TSHRCTSKGAA
SCHEMBL13651409 0.72 CTSK (0.50) CTSKGAA
SCHEMBL12081321 0.72 CTSK (0.50) CTSKGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0797611-B1 ACID ETCH RESISTANT AUTOMOTIVE TOPCOAT KING INDUSTRIES INC (US) 1999-01-27 EP disclosed
EP-0797611-A1 ACID ETCH RESISTANT AUTOMOTIVE TOPCOAT Blank, Werner J. (US) 1997-10-01 EP disclosed
US-5565531-A AUTOMOBILE PROTECTIVE TOPCOATINGS COMPRISING POLYURETHANES HAVING PENDANT ALKYL CHAINS CONTAINING AN ETHER MADE FROM A DICARBAMATE, POLYOL AND ETHER-CONTAINING CARBAMATE; WEATHERPROOFING; DURABILITY; SOLVENT SOLUBILITY KING INDUSTRIES, INC. (US) 1996-10-15 US disclosed
WO-1995032999-A1 ACID ETCH RESISTANT AUTOMOTIVE TOPCOAT BLANK WERNER J (US) 1995-12-07 WO disclosed