⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8371244 | 0.86 | — | — | |
| SCHEMBL28079135 | 0.86 | FBP1 (0.80) | — | |
| SCHEMBL28382830 | 0.84 | FBP1 (0.76) | — | |
| SCHEMBL191350 | 0.81 | FBP1 (1.00) | — | |
| SCHEMBL940049 | 0.77 | — | — | |
| SCHEMBL11829207 | 0.76 | FBP1 (0.81) | — | |
| SCHEMBL11445382 | 0.73 | — | — | |
| Benzene SCHEMBL1358981 | 0.73 | FBP1 (0.58) | — | |
| SCHEMBL9731968 | 0.73 | — | — | |
| SCHEMBL28382686 | 0.72 | FBP1 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124450-A | Reacting solution of 2-mercaptothiazole, saturated secondary heterocyclic amine, sulfur in presence of oxygen, ammonia, copper or cerium catalyst | AKZO N.V. (NL) | 1992-06-23 | — | — | US | claimed |
| EP-0677045-B1 | CATALYTIC OXIDATION PROCESS OF THIOLS | MONSANTO CO (US) | 1999-02-10 | — | — | EP | disclosed |
| CN-1041924-C | Catalytic oxidation process | MONSANTO CO (US) | 1999-02-03 | — | — | CN | disclosed |
| EP-0677045-A1 | CATALYTIC OXIDATION PROCESS | MONSANTO COMPANY (US) | 1995-10-18 | — | — | EP | disclosed |
| CN-1096024-A | catalytic oxidation | MONSANTO CO (US) | 1994-12-07 | — | — | CN | disclosed |
| WO-1994015927-A1 | CATALYTIC OXIDATION PROCESS | MONSANTO COMPANY (US) | 1994-07-21 | — | — | WO | disclosed |
| US-5124450-A | Reacting solution of 2-mercaptothiazole, saturated secondary heterocyclic amine, sulfur in presence of oxygen, ammonia, copper or cerium catalyst | AKZO N.V. (NL) | 1992-06-23 | — | — | US | disclosed |
| US-5124450-A | Reacting solution of 2-mercaptothiazole, saturated secondary heterocyclic amine, sulfur in presence of oxygen, ammonia, copper or cerium catalyst | AKZO N.V. (NL) | 1992-06-23 | — | — | US | disclosed |
| EP-0481366-A1 | Process for the preparation of 2-Aminodithiothiazoles and 2-Aminotrithiothiazoles | Akzo Nobel N.V. (NL) | 1992-04-22 | — | — | EP | disclosed |
| EP-0481366-A1 | Process for the preparation of 2-Aminodithiothiazoles and 2-Aminotrithiothiazoles | Akzo Nobel N.V. (NL) | 1992-04-22 | — | — | EP | disclosed |
| US-4110319-A | NATURAL RUBBER OR DIENE POLYMERS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-08-29 | — | — | US | disclosed |
| US-4087440-A | N-(hydrocarbyl thiophosphoryldithio)-imide vulcanization agents and accelerators | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-05-02 | — | — | US | disclosed |
| US-4085093-A | Sulfilimines as premature vulcanization inhibitors | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-04-18 | — | — | US | disclosed |
| US-4085094-A | SULFENYLTHIOCARBONATES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-04-18 | — | — | US | disclosed |
| US-4042641-A | Inhibiting premature vulcanization of rubbers with N-aryl-hydrocarbyldithio-formimidate | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1977-08-16 | — | — | US | disclosed |
| US-4042642-A | 1,3-BIS(MORPHOLINOTHIO)-IMIDAZOLIDINONE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1977-08-16 | — | — | US | disclosed |
| US-3960857-A | Urea additives for sulfur vulcanizable polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-06-01 | — | — | US | disclosed |
| US-3944552-A | VULCANIZATION | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-03-16 | — | — | US | disclosed |