Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.37 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8372451 | 0.91 | ALDH1A1 (0.48) | ALDH1A3ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL8372772 | 0.90 | ALDH1A1 (0.47) | ALDH1A3ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL8371542 | 0.88 | ALDH1A1 (0.46) | ALDH1A3ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL8376309 | 0.88 | ALDH1A1 (0.46) | ALDH1A3ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL8372766 | 0.88 | ALDH1A1 (0.46) | ALDH1A3ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL8372769 | 0.87 | ALDH1A3 (0.53) | ALDH1A3ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL31395590 | 0.81 | ALDH1A1 (0.49) | ALDH1A3ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL31268591 | 0.79 | TDP1 (0.50) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL1915714 | 0.78 | ALDH1A3 (0.58) | ALDH1A3ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL9151648 | 0.78 | ALDH1A1 (0.46) | ALDH1A3ALDH1A1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802199-B1 | Covalently bound dimers of glycopeptide antibiotics | LILLY CO ELI (US) | 1999-12-08 | — | — | EP | disclosed |
| EP-0802199-A2 | Covalently bound dimers of glycopetide antibiotics | ELI LILLY AND COMPANY (US) | 1997-10-22 | — | — | EP | disclosed |