SCHEMBL8372801

SCHEMBL8372801

C=Cc1ccc(COc2c(N)c(=O)c2=O)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.35
▸ MAPT P10636 3/20 0.33
▸ L3MBTL1 Q9Y468 2/20 0.33
▸ CYP1A2 P05177 1/20 0.33
▸ CYP3A4 P08684 1/20 0.33
▸ CYP2C9 P11712 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33
▸ PTPN2 P17706 1/20 0.33
▸ PTPN1 P18031 1/20 0.33
▸ PTPN11 Q06124 1/20 0.33
▸ MEN1 O00255 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ HIF1A Q16665 1/20 0.32
▸ SIRT2 Q8IXJ6 2/20 0.32
▸ SIRT1 Q96EB6 2/20 0.32
▸ SIRT3 Q9NTG7 2/20 0.32
▸ SIRT5 Q9NXA8 2/20 0.32
▸ LMNA P02545 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.31
▸ POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8644283 0.88 ALDH1A1 (0.42) ALDH1A1MAPTL3MBTL1CYP1A2CYP3A4
SCHEMBL8640810 0.77 HIF1A (0.35) ALDH1A1MAPTL3MBTL1CYP1A2CYP3A4
SCHEMBL14867055 0.73 MAPT (0.41) ALDH1A1MAPTL3MBTL1CYP1A2CYP3A4
SCHEMBL14655816 0.73 ALDH1A1 (0.41) ALDH1A1MAPTL3MBTL1CYP1A2HIF1A
SCHEMBL8642948 0.72 THRB (0.38) ALDH1A1MAPTCYP3A4MEN1KMT2A
SCHEMBL18546472 0.71 MAOB (0.61) MAPTL3MBTL1PTPN2PTPN1PTPN11
SCHEMBL6389116 0.71 MAPT (0.42) ALDH1A1MAPTL3MBTL1CYP1A2CYP3A4
SCHEMBL6388039 0.71 APP (0.54) ALDH1A1PTPN2PTPN1PTPN11CHRNB2
SCHEMBL13242652 0.71 APP (0.54) ALDH1A1PTPN2PTPN1PTPN11CHRNB2
SCHEMBL6394555 0.70 ALDH1A1 (0.46) ALDH1A1CYP1A2MEN1KMT2AHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0665789-B1 HEAT-SENSITIVE IMAGE RECORDING MEDIUM AND PROCESS POLAROID CORP (US) 1997-01-22 — — EP claimed
EP-0665789-A1 HEAT-SENSITIVE IMAGE RECORDING MEDIUM AND PROCESS. POLAROID CORP (US) 1995-08-09 — — EP claimed
US-5334489-A Hydroxylating 3,4-disubstituted-cyclobut-3-ene-1,2-dione by heating in presence of acid catalysts which is generated by exposing actinic radiation from superacid precursor POLAROID CORPORATION (US) 1994-08-02 — — US claimed
WO-1994009992-A1 HEAT-SENSITIVE IMAGE RECORDING MEDIUM AND PROCESS POLAROID CORPORATION (US) 1994-05-11 — — WO claimed
US-6004719-A ACID-GENERATING LAYER OR PHASE COMPRISING A MIXTURE OF A SUPERACID PRECURSOR, A SENSITIZING DYE AND A SECONDARY ACID GENERATOR, AND A COLOR-CHANGE LAYER OR PHASE COMPRISING AN IMAGE DYE. POLAROID CORPORATION (US) 1999-12-21 — — US disclosed
EP-0757629-B1 IMAGING MEDIUM AND PROCESS POLAROID CORP (US) 1999-01-20 — — EP disclosed
EP-0757628-B1 PROCESS FOR FIXING AN IMAGE POLAROID CORP (US) 1998-12-02 — — EP disclosed
EP-0665960-B1 IMAGING MEDIUM AND PROCESS POLAROID CORP (US) 1998-08-19 — — EP disclosed
US-5741630-A ACID-CATALYZED THERMAL DECOMPOSITION OF SECONDARY ACID GENERATOR AND FORMATION OF SECOND ACID; COPPER COMPOUND AND REACTIVE MATERIAL USED TO DECOMPOSE SUPERACID PRECURSOR POLAROID CORPORATION (US) 1998-04-21 — — US disclosed
US-5667943-A SQUARIC ACID DERIVATIVES, LEUCO DYES POLAROID CORPORATION (US) 1997-09-16 — — US disclosed
US-5631118-A MULTILAYER ELEMENT WITH ACID GENERATING LAYER, ACID PRECURSOR, SENSITIZING DYE, ACID GENERATOR AND COLOR CHANGING LAYER POLAROID CORPORATION (US) 1997-05-20 — — US disclosed
EP-0757629-A1 IMAGING MEDIUM AND PROCESS POLAROID CORPORATION (US) 1997-02-12 — — EP disclosed
US-5401607-A Iodonium salt and squarylium dye with pyrilium group for acid formation POLAROID CORPORATION (US) 1995-03-28 — — US disclosed
US-5395736-A Exposing superoxide precursor to actinic radiation, generating superacid, mixing with oxalic acid diester, heating POLAROID CORPORATION (US) 1995-03-07 — — US disclosed
US-5334489-A Hydroxylating 3,4-disubstituted-cyclobut-3-ene-1,2-dione by heating in presence of acid catalysts which is generated by exposing actinic radiation from superacid precursor POLAROID CORPORATION (US) 1994-08-02 — — US disclosed
WO-1994010606-A1 IMAGING MEDIUM AND PROCESS POLAROID CORPORATION (US) 1994-05-11 — — WO disclosed
WO-1994010607-A1 IMAGING MEDIUM AND PROCESS POLAROID CORPORATION (US) 1994-05-11 — — WO disclosed
WO-1994009992-A1 HEAT-SENSITIVE IMAGE RECORDING MEDIUM AND PROCESS POLAROID CORPORATION (US) 1994-05-11 — — WO disclosed
US-5286612-A Mixture of superacid precursor and dye POLAROID CORPORATION (US) 1994-02-15 — — US disclosed
US-5278031-A Neutralization of acid compounds and reverse coloring POLAROID CORPORATION (US) 1994-01-11 — — US disclosed
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