Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425728 | 0.88 | TAAR1 (0.52) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL27144 | 0.88 | ALDH1A1 (0.68) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL6309750 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL28251886 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL4219390 | 0.83 | ELANE (0.56) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL697595 | 0.82 | KMT2A (0.60) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL10597179 | 0.82 | KMT2A (0.71) | ALDH1A1TDP1KMT2AL3MBTL1SLC6A2 | |
| Diphenyl Ethanedioat SCHEMBL43364 | 0.81 | TDP1 (0.54) | ALDH1A1TDP1L3MBTL1HSD17B10TSHR | |
| SCHEMBL11128305 | 0.80 | ALDH1A1 (0.59) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL931107 | 0.79 | ALDH1A1 (0.63) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1260227-C | 5-membered ring heterocyclic compounds with nitrogen | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2006-06-21 | — | — | CN | disclosed |
| CN-1413207-A | 5-membered ring heterocyclic compounds with nitrogen | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-04-23 | — | — | CN | disclosed |
| EP-0950418-A2 | Composition for preventing or treating ischemic disease | Takeda Chemical Industries, Ltd. (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5599823-A | HYPOTENSIVE AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-04 | — | — | US | disclosed |
| US-5462851-A | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1995-10-31 | — | — | US | disclosed |
| US-5238909-A | For preemergence or postemergence use | EASTMAN KODAK COMPANY (US) | 1993-08-24 | — | — | US | disclosed |
| EP-0273659-A1 | Azaspiro compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-07-06 | — | — | EP | disclosed |
| EP-0148883-A1 | ALLOPURINOL PRODRUGS. | GEA AS (DK) | 1985-07-24 | — | — | EP | disclosed |
| WO-1985000368-A1 | ALLOPURINOL PRODRUGS | A/S GEA (DK) | 1985-01-31 | — | — | WO | disclosed |