Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 5/20 | 0.48 |
| ▸ | PPARA | Q07869 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8372844 | 0.88 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1L3MBTL1NR4A2 | |
| SCHEMBL28142 | 0.80 | IDO1 (0.52) | ALDH1A1KMT2AMAPTMEN1L3MBTL1 | |
| SCHEMBL27144 | 0.80 | ALDH1A1 (0.68) | ALDH1A1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL20023010 | 0.80 | ADAMTS5 (0.52) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL2706424 | 0.79 | NPC1 (0.56) | ALDH1A1KMT2AMAPTMEN1L3MBTL1 | |
| SCHEMBL10597179 | 0.79 | KMT2A (0.71) | ALDH1A1KMT2AMAPTMEN1L3MBTL1 | |
| SCHEMBL7063178 | 0.78 | ELANE (0.50) | TAAR1KMT2AMAPTMEN1CYP1A2 | |
| SCHEMBL20022989 | 0.78 | TAAR1 (0.50) | TAAR1ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL6647703 | 0.78 | ALDH1A1 (0.60) | ALDH1A1KMT2AMAPTMEN1L3MBTL1 | |
| SCHEMBL4955275 | 0.77 | NPC1 (0.55) | ALDH1A1KMT2AMAPTMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0809644-A1 | 4-SUBSTITUTED CEPHEM DERIVATIVES AS ELASTASE INHIBITORS | PHARMACIA & UPJOHN S.p.A. (IT) | 1997-12-03 | — | — | EP | claimed |
| WO-1997022609-A1 | 4-SUBSTITUTED CEPHEM DERIVATIVES AS ELASTASE INHIBITORS | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-06-26 | — | — | WO | claimed |