Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8371974 | 0.85 | ADRA2A (0.45) | ADRA2AADRA2BADRA2CHDAC8HDAC6 | |
| SCHEMBL20032404 | 0.83 | SLC6A4 (0.63) | ADRA2AADRA2BADRA2CHDAC8HDAC6 | |
| SCHEMBL30180008 | 0.79 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CHDAC8HDAC6 | |
| SCHEMBL20892300 | 0.79 | ESR1 (0.38) | ADRA2AADRA2BADRA2CHDAC8HDAC6 | |
| SCHEMBL943047 | 0.78 | ALDH1A1 (0.47) | HDAC8SLC6A4MAPTALOX15CYP2C9 | |
| SCHEMBL10014257 | 0.78 | ADRA2A (0.40) | ADRA2AADRA2BADRA2CHDAC8HDAC6 | |
| SCHEMBL3989199 | 0.74 | ADRA2A (0.48) | ADRA2AADRA2BADRA2CHDAC8HDAC6 | |
| SCHEMBL24293770 | 0.73 | PTGIR (0.46) | MAPTCYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL14174730 | 0.73 | ADRA2A (0.41) | ADRA2AADRA2BADRA2CHDAC8HDAC6 | |
| SCHEMBL2963901 | 0.72 | ADRA2A (0.47) | ADRA2AADRA2BADRA2CHDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0896050-A1 | Lubricating oil composition comprising a specific base oil and an oxidation inhibitor | NIPPON OIL CO., LTD. (JP) | 1999-02-10 | — | — | EP | disclosed |