Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | EDNRB | P24530 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750486 | 1.00 | EDNRA (0.43) | EDNRACA1CA2EDNRBCES2 | |
| SCHEMBL8776894 | 1.00 | EDNRA (0.43) | EDNRACA1CA2EDNRBCES2 | |
| SCHEMBL16109514 | 0.85 | OPRK1 (0.46) | CA1CA2GAAMAPTL3MBTL1 | |
| SCHEMBL14967580 | 0.82 | EDNRA (0.43) | EDNRAEDNRBCES2CES1GAA | |
| SCHEMBL9750496 | 0.81 | MEN1 (0.47) | CES2CES1GAAALDH1A1TSHR | |
| SCHEMBL9469474 | 0.81 | MAPK1 (0.38) | CES2CES1GAAMAPTMAOB | |
| SCHEMBL329169 | 0.80 | KMT2A (0.40) | MAPTMAOBL3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL16108680 | 0.80 | ALDH1A1 (0.50) | GAAALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL16109774 | 0.80 | ALDH1A1 (0.40) | EDNRAEDNRBCES2CES1GAA | |
| SCHEMBL16108693 | 0.80 | HPGD (0.43) | EDNRAEDNRBCES2CES1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6335399-A | — | — | None | — | — | JP | disclosed |
| EP-0602740-B1 | Process for the enzymatic preparation of optically active transglycidic acid esters | DSM NV (NL) | 1999-02-24 | — | — | EP | disclosed |
| US-5407828-A | Hydrolysis; separation of non-hydrolyzed enantiomorph | DSM N.V. (NL) | 1995-04-18 | — | — | US | disclosed |
| JP-H06335399-A | PRODUCTION OF OPTICALLY ACTIVE ESTER OF TRANS-3-PHENYLGLYCIDIC ACID AND PRODUCTION OF BENZO(THI)AZEPINE | DSM NV | 1994-12-06 | — | — | JP | disclosed |
| EP-0343714-B1 | Phenylglycidate stereoisomers, conversion products thereof with e.g. 2-nitrothiophenol and preparation of diltiazem | DSM NV (NL) | 1994-11-02 | — | — | EP | disclosed |
| EP-0602740-A1 | Process for the enzymatic preparation of optically active transglycidic acid esters | DSM N.V. (NL) | 1994-06-22 | — | — | EP | disclosed |
| EP-0343714-A1 | Phenylglycidate stereoisomers, conversion products thereof with e.g. 2-nitrothiophenol and preparation of diltiazem | DSM N.V. (NL) | 1989-11-29 | — | — | EP | disclosed |