SCHEMBL8373496

SCHEMBL8373496

C[Ti](C)(C)(C)(=[SiH2])(c1cccc2c1Cc1ccccc1-2)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.47
NPC1 O15118 2/20 0.47
PNMT P11086 1/20 0.46
HTR2B P41595 2/20 0.38
HTR7 P34969 1/20 0.38
HIF1A Q16665 2/20 0.36
PGR P06401 1/20 0.36
PDGFRB P09619 1/20 0.36
MAOA P21397 2/20 0.35
EIF2AK1 Q9BQI3 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8373678 0.84 RAB9A (0.42) RAB9ANPC1PNMTHTR2BHTR7
SCHEMBL8373279 0.80 PNMT (0.42) RAB9ANPC1PNMTHTR2BHTR7
SCHEMBL7919498 0.79 RAB9A (0.40) RAB9ANPC1PNMTHTR2BHTR7
SCHEMBL7927604 0.78 RAB9A (0.48) RAB9ANPC1PNMTHTR2BHTR7
SCHEMBL524602 0.76 PNMT (0.63) RAB9ANPC1PNMTHTR2BHTR7
SCHEMBL30103334 0.76 PNMT (0.63) RAB9ANPC1PNMTHTR2BHTR7
SCHEMBL7927235 0.76 RAB9A (0.43) RAB9ANPC1PNMTHTR2BHTR7
SCHEMBL7930733 0.75 RAB9A (0.42) RAB9ANPC1PNMTHTR2BHTR7
SCHEMBL2877998 0.74 PNMT (0.61) RAB9ANPC1PNMTHTR2BHTR7
SCHEMBL22263591 0.71 PNMT (0.57) RAB9ANPC1PNMTHTR2BHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0659774-B1 Process for producing styrenic polymer IDEMITSU KOSAN CO (JP) 1999-03-03 EP disclosed
EP-0707014-B1 PROCESS FOR PRODUCING AROMATIC VINYL COMPOUND COPOLYMER IDEMITSU KOSAN CO (JP) 1999-02-17 EP disclosed
US-5747613-A Process for producing aromatic vinyl compound-based copolymer IDEMITSU KOSAN CO., LTD. (JP) 1998-05-05 US disclosed
US-5623034-A Process for producing styrenic polymer IDEMITSU KOSAN CO., LTD. (JP) 1997-04-22 US disclosed
EP-0497207-B1 Process for purification of styrenic polymer IDEMITSU KOSAN CO (JP) 1996-11-20 EP disclosed
EP-0707014-A1 PROCESS FOR PRODUCING AROMATIC VINYL COMPOUND COPOLYMER IDEMITSU KOSAN COMPANY LIMITED (JP) 1996-04-17 EP disclosed
EP-0659774-A2 Process for producing styrenic polymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1995-06-28 EP disclosed