Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | SCN1A | P35498 | 1/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.47 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19219007 | 0.89 | ALDH1A1 (0.62) | MAPTALDH1A1LMNASMN1; SMN2RAB9A | |
| SCHEMBL14089606 | 0.88 | MAPT (0.47) | MAPTALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL21908332 | 0.87 | THRB (0.55) | MAPTALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL20464827 | 0.86 | MAPT (0.58) | MAPTALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL19214420 | 0.85 | ALDH1A1 (0.61) | MAPTALDH1A1LMNASMN1; SMN2PKM | |
| SCHEMBL210094 | 0.85 | MAPT (0.77) | MAPTALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL23928035 | 0.84 | ALDH1A1 (0.56) | MAPTALDH1A1LMNASMN1; SMN2RAB9A | |
| SCHEMBL19218159 | 0.84 | ALDH1A1 (0.56) | MAPTALDH1A1LMNASMN1; SMN2RAB9A | |
| SCHEMBL23928034 | 0.84 | ALDH1A1 (0.56) | MAPTALDH1A1LMNASMN1; SMN2RAB9A | |
| SCHEMBL17466188 | 0.84 | ALDH1A1 (0.43) | MAPTALDH1A1LMNAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802199-B1 | Covalently bound dimers of glycopeptide antibiotics | LILLY CO ELI (US) | 1999-12-08 | — | — | EP | disclosed |
| EP-0801075-B1 | Covalently linked dimers of glycopeptide antibiotics | LILLY CO ELI (US) | 1999-07-07 | — | — | EP | disclosed |