Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10875389 | 0.86 | LMNA (0.68) | LMNASMN1; SMN2CYP1A2KDM4ECYP2C9 | |
| SCHEMBL16342153 | 0.80 | LMNA (0.49) | LMNASMN1; SMN2CYP1A2KDM4ECYP2C9 | |
| SCHEMBL22680970 | 0.76 | LMNA (0.68) | LMNASMN1; SMN2CYP1A2KDM4ECYP2C9 | |
| SCHEMBL9852541 | 0.75 | LMNA (0.61) | LMNASMN1; SMN2CYP1A2KDM4ECYP2C9 | |
| Diatrizoic Acid SCHEMBL8508 | 0.74 | LMNA (0.67) | LMNASMN1; SMN2KDM4EHSD17B10MEN1 | |
| SCHEMBL9298885 | 0.74 | LMNA (0.66) | LMNASMN1; SMN2CYP1A2KDM4ECYP2C9 | |
| Diatrizoic Acid SCHEMBL7615048 | 0.74 | LMNA (0.67) | LMNASMN1; SMN2KDM4EHSD17B10MEN1 | |
| SCHEMBL3082732 | 0.72 | LMNA (0.63) | LMNASMN1; SMN2CYP1A2KDM4ECYP2C9 | |
| SCHEMBL9816383 | 0.72 | LMNA (0.53) | LMNASMN1; SMN2CYP1A2KDM4ECYP2C9 | |
| Diatrizoic Acid SCHEMBL8509 | 0.72 | LMNA (0.65) | LMNASMN1; SMN2KDM4EHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958376-A | Iodinated X-ray contrast media | NYCOMED IMAGING AS (NO) | 1999-09-28 | — | — | US | disclosed |
| US-5958375-A | Urea-linked, iodinated bis phenyl compounds for X-ray contrast media | NYCOMED IMAGING AS (NO) | 1999-09-28 | — | — | US | disclosed |
| EP-0782565-B1 | IODINATED X-RAY-CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1999-04-07 | — | — | EP | disclosed |
| EP-0782565-A1 | IODINATED X-RAY-CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1997-07-09 | — | — | EP | disclosed |
| WO-1996009285-A1 | IODINATED X-RAY-CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1996-03-28 | — | — | WO | disclosed |