Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255096 | 0.83 | LMNA (0.40) | LMNA | |
| SCHEMBL8374104 | 0.80 | LMNA (0.55) | LMNASMN1; SMN2KDM4ECYP1A2CYP2C9 | |
| SCHEMBL10875389 | 0.79 | LMNA (0.68) | LMNASMN1; SMN2KDM4ECYP1A2CYP2C9 | |
| SCHEMBL9816387 | 0.75 | LMNA (0.53) | LMNASMN1; SMN2KDM4ECYP1A2CYP2C9 | |
| SCHEMBL20471520 | 0.71 | LMNA (0.48) | LMNASMN1; SMN2KDM4ECYP1A2CYP2C9 | |
| SCHEMBL22680970 | 0.70 | LMNA (0.68) | LMNASMN1; SMN2KDM4ECYP1A2CYP2C9 | |
| SCHEMBL10877148 | 0.70 | LMNA (0.52) | LMNASMN1; SMN2KDM4ECYP1A2CYP2C9 | |
| SCHEMBL9852541 | 0.69 | LMNA (0.61) | LMNASMN1; SMN2KDM4ECYP1A2CYP2C9 | |
| SCHEMBL16418460 | 0.69 | LMNA (0.35) | LMNASMN1; SMN2 | |
| SCHEMBL8600920 | 0.68 | LMNA (0.46) | LMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230321284-A1 | COMPOUND, CONTRAST AGENT, AND METHOD FOR PRODUCING COMPOUND | ST. MARIANNA UNIVERSITY SCHOOL OF MEDICINE (JP) | 2023-10-12 | — | — | US | disclosed |
| US-9387267-B2 | Iodine-containing radial-shaped macromolecular compounds, preparation method thereof and contrast media compositions for CT comprising the same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2016-07-12 | — | — | US | disclosed |
| US-20130150529-A1 | IODINE-CONTAINING RADIAL-SHAPED MACROMOLECULAR COMPOUNDS, PREPARATION METHOD THEREOF AND CONTRAST MEDIA COMPOSITIONS FOR CT COMPRISING THE SOME | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2013-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150529-A1 | IODINE-CONTAINING RADIAL-SHAPED MACROMOLECULAR COMPOUNDS, PREPARATION METHOD THEREOF AND CONTRAST MEDIA COMPOSITIONS FOR CT COMPRISING THE SOME | IGFBP1, IGFBP5, IGFBP2 | LMNA 2428/4885SMN1; SMN2 4875/4885KDM4E 4383/4885 |
| US-20230321284-A1 | COMPOUND, CONTRAST AGENT, AND METHOD FOR PRODUCING COMPOUND | RXFP1, AVPR2, RXFP3 | LMNA 3418/4885SMN1; SMN2 2432/4885KDM4E 4339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.