SCHEMBL8374339

SCHEMBL8374339

CCCCCCC(F)COc1ccc(O)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.60
LTA4H P09960 4/20 0.53
SLC2A1 P11166 1/20 0.43
PLA2G4B P0C869 1/20 0.43
ESR1 P03372 7/20 0.42
SLC6A2 P23975 3/20 0.42
ADRA2A P08913 2/20 0.42
ADORA3 P0DMS8 2/20 0.42
TACR2 P21452 2/20 0.42
SLC6A4 P31645 2/20 0.42
SLC6A3 Q01959 2/20 0.42
PTGS1 P23219 2/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
SHBG P04278 1/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
HSPD1 P10809 1/20 0.42
ADRB3 P13945 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9124506 0.96 NR5A1 (0.55) NR5A1LTA4HSLC2A1PLA2G4BESR1
SCHEMBL9124494 0.96 NR5A1 (0.55) NR5A1LTA4HSLC2A1PLA2G4BESR1
SCHEMBL9049888 0.94 NR5A1 (0.53) NR5A1LTA4HSLC2A1PLA2G4BESR1
SCHEMBL9502936 0.94 LTA4H (0.54) NR5A1LTA4HSLC2A1PLA2G4BESR1
SCHEMBL7795401 0.86 RAB9A (0.47) NR5A1LTA4HPLA2G4BESR1KDM4E
SCHEMBL1582923 0.84 KDM4E (0.50) NR5A1LTA4HSLC2A1PLA2G4BKDM4E
SCHEMBL9148171 0.84 LTA4H (0.49) LTA4HSLC2A1PLA2G4BESR1SLC6A2
SCHEMBL9145900 0.84 LTA4H (0.49) LTA4HSLC2A1PLA2G4BESR1SLC6A2
SCHEMBL7794972 0.84 NR5A1 (0.42) NR5A1LTA4HESR1SLC6A2ADRA2A
SCHEMBL8020825 0.83 RARB (0.52) NR5A1LTA4HSLC2A1PLA2G4BKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1160986-A None JP disclosed
EP-0626438-B1 Mesomorphic compound, liquid crystal composition and liquid crystal device CANON KK (JP) 1999-03-10 EP disclosed
EP-0460624-B1 Liquid crystal composition, liquid crystal device, display apparatus and display method CANON KK (JP) 1997-09-10 EP disclosed
EP-0440136-B1 Liquid crystal composition and liquid crystal device containing the same CANON KK (JP) 1997-04-02 EP disclosed
US-5614125-A POLYMERS FOR OPTICAL DEVICES FOR DISPLAYS CANON KABUSHIKI KAISHA (JP) 1997-03-25 US disclosed
US-5599479-A Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1997-02-04 US disclosed
EP-0412485-B1 Polymeric liquid-crystal composition and polymeric liquid-crystal device CANON KK (JP) 1997-01-22 EP disclosed
EP-0458347-B1 Liquid crystal composition and display device using same CANON KK (JP) 1996-09-11 EP disclosed
EP-0499252-B1 Liquid crystal composition, liquid crystal device, display apparatus and display method CANON KK (JP) 1996-09-11 EP disclosed
US-5501818-A PYRIMIDINE COMPOUNDS, IMPROVED RESPONSE SPEED WITH LESS TEMPERATURE DEPENDENCE CANON KABUSHIKI KAISHA (JP) 1996-03-26 US disclosed
EP-0355374-A2 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1990-02-28 EP disclosed
EP-0352479-A2 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1990-01-31 EP disclosed
EP-0351587-A2 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1990-01-24 EP disclosed
EP-0348873-A2 Ferroelectric liquid-crystalline polymer and epoxide usable for preparing the ferroelectric liquid-crystalline polymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-01-03 EP disclosed
EP-0347942-A2 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1989-12-27 EP disclosed
EP-0347944-A2 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1989-12-27 EP disclosed
EP-0347940-A2 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1989-12-27 EP disclosed
EP-0322703-A2 Mesomorphic compound, liquid crystal composition and liquid crystal device CANON KABUSHIKI KAISHA (JP) 1989-07-05 EP disclosed
JP-H01160986-A LIQUID CRYSTAL COMPOUND, ITS PRODUCTION AND COMPOSITION THEREOF NOHIRA HIROYUKI 1989-06-23 JP disclosed
EP-0315958-A2 Optically active mesomorphic compound and liquid crystal composition containing same CANON KABUSHIKI KAISHA (JP) 1989-05-17 EP disclosed