SCHEMBL8374684

SCHEMBL8374684

CCCC(=O)OC(=O)CC(C)(C)S

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.62
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
PRSS1 P07477 1/20 0.33
CTSG P08311 1/20 0.33
CTRB1 P17538 1/20 0.33
CMA1 P23946 1/20 0.33
LMNA P02545 1/20 0.33
FFAR3 O14843 3/20 0.32
HDAC3 O15379 3/20 0.32
HDAC1 Q13547 3/20 0.32
HDAC2 Q92769 3/20 0.32
HDAC8 Q9BY41 3/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8374682 0.87 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL385887 0.83 ALDH1A1 (0.68) ALDH1A1CES2CES1PRSS1CTSG
SCHEMBL30568759 0.79 ALDH1A1 (1.00) ALDH1A1CES2CES1LMNAFFAR3
SCHEMBL8158 0.79 ALDH1A1 (1.00) ALDH1A1CES2CES1LMNAFFAR3
SCHEMBL27500855 0.77 ALDH1A1 (0.65) ALDH1A1CES2CES1LMNAFFAR3
SCHEMBL9556715 0.77 ALDH1A1 (0.94) ALDH1A1CES2CES1LMNAFFAR3
SCHEMBL17477083 0.77 ALDH1A1 (0.94) ALDH1A1CES2CES1LMNAFFAR3
SCHEMBL28174826 0.77 ALDH1A1 (0.94) ALDH1A1CES2CES1LMNAFFAR3
SCHEMBL10640242 0.77 ALDH1A1 (0.94) ALDH1A1CES2CES1LMNAFFAR3
Methyl Alcohol SCHEMBL27968813 0.77 ALDH1A1 (0.94) ALDH1A1CES2CES1LMNAFFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999060187-A1 METAL SURFACE TREATMENT AGENTS, METHODS OF TREATING METAL SURFACES AND PRE-COATED STEEL SHEETS DACRAL S.A. (FR) 1999-11-25 WO disclosed