SCHEMBL8374682

SCHEMBL8374682

CC(C)(S)CC(=O)OC(=O)CC(C)(C)S

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
TSHR P16473 2/20 0.32
HSD17B10 Q99714 1/20 0.32
HMGCR P04035 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
ADRA1A P35348 1/20 0.32
TET2 Q6N021 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8374684 0.87 ALDH1A1 (0.62) ALDH1A1TSHR
SCHEMBL2854781 0.81
SCHEMBL869221 0.79 DGKA (0.37) ALDH1A1TSHRCHRM1TBXA2RADRA1A
SCHEMBL27968609 0.77 GAA (0.50) ALDH1A1HSD17B10CYP2C19
SCHEMBL385886 0.77 ALDH1A1 (0.41) ALDH1A1TSHRHMGCRCHRM1TBXA2R
SCHEMBL869482 0.75 MAPK1 (0.32) HIF1A
SCHEMBL1756074 0.75 NAAA (0.43) ALDH1A1TSHRADRA1A
SCHEMBL8373337 0.74 ALDH1A1 (0.46) ALDH1A1TSHR
SCHEMBL19433047 0.74 ALDH1A1 (0.35) ALDH1A1TSHRHSD17B10ADRA1AHIF1A
SCHEMBL15796672 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999060187-A1 METAL SURFACE TREATMENT AGENTS, METHODS OF TREATING METAL SURFACES AND PRE-COATED STEEL SHEETS DACRAL S.A. (FR) 1999-11-25 WO disclosed