SCHEMBL8375152

SCHEMBL8375152

CN(C=C1CC=NC(N)=C1O)C1CCCCC1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADH1C P00326 1/20 0.34
ADH1A P07327 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8375879 0.78 ITGB1 (0.32) ADH1CADH1A
SCHEMBL8375153 0.61 ADH1C (0.34) ADH1CADH1A
SCHEMBL11176820 0.57 ADH1C (0.39) ADH1CADH1A
SCHEMBL7534361 0.54 ADH1A (0.58) ADH1CADH1A
SCHEMBL11832867 0.54 ADH1A (0.58) ADH1CADH1A
SCHEMBL7536596 0.54 ADH1A (0.58) ADH1CADH1A
SCHEMBL1679242 0.54 ADH1A (1.00) ADH1CADH1A
SCHEMBL1535987 0.54 ADH1A (0.58) ADH1CADH1A
SCHEMBL7533870 0.54 ADH1A (0.58) ADH1CADH1A
SCHEMBL1678872 0.54 ADH1A (1.00) ADH1CADH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5821239-A USEFUL FOR TREATING ALZHEIMER'S DISEASE CAUSED BY CHOLINERGIC DEFICIT FROMMER LAWRENCE & HUAG LLP (US) 1998-10-13 US claimed
US-5869480-A ALLEVIATING MEMORY DYSFUNCTION CHARACTERIZED BY CHOLINERGIC DEFICIT HOECHST MARION ROUSSEL INC. (US) 1999-02-09 US disclosed
US-5866565-A ALZHEIMER'S DISORDERS HOECHST MARION ROUSSEL INC. (US) 1999-02-02 US disclosed
US-5821239-A USEFUL FOR TREATING ALZHEIMER'S DISEASE CAUSED BY CHOLINERGIC DEFICIT FROMMER LAWRENCE & HUAG LLP (US) 1998-10-13 US disclosed