Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Clopidol SCHEMBL661598 | 1.00 | TSHR (0.44) | TSHRHPGDHSD17B10LMNAMEN1 | |
| Clopidol SCHEMBL28541417 | 0.97 | TSHR (0.42) | TSHRHPGDHSD17B10LMNAMEN1 | |
| Clopidol SCHEMBL28662687 | 0.97 | TSHR (0.42) | TSHRHPGDHSD17B10LMNAMEN1 | |
| Clopidol SCHEMBL29040982 | 0.97 | TSHR (0.42) | TSHRHPGDHSD17B10LMNAMEN1 | |
| SCHEMBL7608160 | 0.88 | LMNA (0.33) | TSHRHPGDHSD17B10LMNAMEN1 | |
| Clopidol SCHEMBL27959733 | 0.87 | MEN1 (0.35) | TSHRHPGDHSD17B10LMNAMEN1 | |
| Clopidol SCHEMBL8172676 | 0.87 | MEN1 (0.35) | TSHRHPGDHSD17B10LMNAMEN1 | |
| SCHEMBL11529648 | 0.82 | HPGD (0.40) | TSHRHPGDHSD17B10LMNAMEN1 | |
| SCHEMBL10328314 | 0.78 | MEN1 (0.32) | TSHRHPGDHSD17B10LMNAMEN1 | |
| SCHEMBL28462818 | 0.77 | ALDH1A1 (0.41) | TSHRHPGDMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0896535-A1 | USE OF SUBSTITUTED ARYL IMIDAZOLES | BAYER AG (DE) | 1999-02-17 | — | — | EP | disclosed |
| WO-1997036582-A1 | USE OF SUBSTITUTED ARYL IMIDAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-10-09 | — | — | WO | disclosed |