SCHEMBL8375317

SCHEMBL8375317

CC(=O)Oc1ccc([P+](C)(c2ccc(OC(C)=O)cc2)c2ccc(OC(C)=O)cc2)cc1.CC(=O)Oc1ccc([P+](C)(c2ccc(OC(C)=O)cc2)c2ccc(OC(C)=O)cc2)cc1.O=[Mn](=O)(O)Cl.O=[Mn](=O)(O)Cl.O=[Mn](=O)([O-])Cl.O=[Mn](=O)([O-])Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.45
POLB P06746 1/20 0.45
PKM P14618 1/20 0.45
LMNA P02545 4/20 0.44
ELANE P08246 3/20 0.44
HSD17B10 Q99714 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
GAA P10253 2/20 0.38
ALDH1A1 P00352 1/20 0.38
HSP90AA1 P07900 1/20 0.38
KDM4E B2RXH2 3/20 0.37
CYP3A4 P08684 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
TTR P02766 1/20 0.37
TP53 P04637 1/20 0.37
GLA P06280 1/20 0.36
ESR1 P03372 2/20 0.36
SLC6A3 Q01959 2/20 0.36
PGR P06401 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8378606 0.94 ELANE (0.46) MAPTPOLBPKMLMNAELANE
SCHEMBL8375313 0.82 LMNA (0.52) MAPTPOLBPKMLMNAELANE
SCHEMBL8602216 0.82 LMNA (0.52) MAPTPOLBPKMLMNAELANE
SCHEMBL8372540 0.82 LMNA (0.52) MAPTPOLBPKMLMNAELANE
SCHEMBL8373309 0.82 LMNA (0.52) MAPTPOLBPKMLMNAELANE
SCHEMBL8374662 0.78 MAPT (0.45) MAPTPOLBPKMLMNAELANE
SCHEMBL8375286 0.76 ADRB2 (0.38) MAPTPOLBLMNAMEN1KMT2A
SCHEMBL8375975 0.76 GAA (0.54) MAPTPOLBPKMLMNAELANE
SCHEMBL8378603 0.76 ELANE (0.53) MAPTPOLBPKMLMNAELANE
SCHEMBL8373308 0.76 ELANE (0.53) MAPTPOLBPKMLMNAELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0718706-B1 Bis(quaternary phosphonium) tetrahalomanganate salts as charge-control agents EASTMAN KODAK CO (US) 1999-03-17 EP disclosed
EP-0718706-A1 Bis(quaternary phosphonium) tetrahalomanganate salts as charge-control agents EASTMAN KODAK COMPANY (US) 1996-06-26 EP disclosed
US-5512407-A Bis(quaternary phosphonium) tetrahalomanganate salts as charge-control agents EASTMAN KODAK COMPANY (US) 1996-04-30 US disclosed