SCHEMBL8375335

SCHEMBL8375335

CCC(O)NOC(=O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
ALDH1A1 P00352 5/20 0.49
KMT2A Q03164 3/20 0.49
POLB P06746 1/20 0.49
MAPT P10636 1/20 0.49
LMNA P02545 2/20 0.47
ADRB2 P07550 2/20 0.45
ADRB1 P08588 2/20 0.45
ADRB3 P13945 2/20 0.45
F2 P00734 1/20 0.44
RAB9A P51151 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
NPC1 O15118 2/20 0.42
GAA P10253 1/20 0.42
TDP1 Q9NUW8 3/20 0.42
TP53 P04637 1/20 0.42
SLC6A3 Q01959 2/20 0.41
HTR1A P08908 1/20 0.41
CYP2D6 P10635 1/20 0.41
SCN1A P35498 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23522306 0.83 ALDH1A1 (0.51) TSHRALDH1A1KMT2APOLBMAPT
SCHEMBL9843494 0.80 ALDH1A1 (0.50) TSHRALDH1A1KMT2APOLBMAPT
SCHEMBL3496640 0.78 ALDH1A1 (0.68) TSHRALDH1A1KMT2APOLBMAPT
SCHEMBL28773960 0.78 TSHR (0.48) TSHRALDH1A1KMT2APOLBMAPT
SCHEMBL27727622 0.76 LMNA (0.56) TSHRALDH1A1KMT2APOLBMAPT
SCHEMBL27727625 0.75 TSHR (0.59) TSHRALDH1A1KMT2APOLBMAPT
SCHEMBL25582979 0.75 TSHR (0.53) TSHRALDH1A1KMT2APOLBMAPT
SCHEMBL25583054 0.75 TSHR (0.48) TSHRALDH1A1KMT2APOLBMAPT
SCHEMBL3492756 0.74 TSHR (0.57) TSHRALDH1A1KMT2APOLBMAPT
SCHEMBL26461278 0.74 TSHR (0.52) TSHRALDH1A1KMT2APOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0552289-A4 PREVENTION OR TREATMENT OF SUNBURN USING THE S(+) ISOMER OF KETOPROFEN 1993-08-11 EP claimed
EP-0552289-A1 PREVENTION OR TREATMENT OF SUNBURN USING THE S(+) ISOMER OF KETOPROFEN MILES INC. (US) 1993-07-28 EP claimed
WO-1992005769-A1 PREVENTION OR TREATMENT OF SUNBURN USING THE S(+) ISOMER OF KETOPROFEN MILES, INC. (US) 1992-04-16 WO claimed
WO-1991017740-A1 PREVENTION OR TREATMENT OF SUNBURN USING THE S(+) ISOMER OF FLURBIPROFEN ANALGESIC ASSOCIATES (US) 1991-11-28 WO claimed
CN-102356121-A Uv and light protective film HUHTAMAKI FORCHHEIM 2012-02-15 CN disclosed
EP-0901512-A1 DETERGENT COMPOSITION UNILEVER PLC (GB) 1999-03-17 EP disclosed
WO-1997044422-A1 DETERGENT COMPOSITION UNILEVER PLC (GB) 1997-11-27 WO disclosed