Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8517656 | 0.85 | GAA (0.41) | ALDH1A1MEN1MAPTKMT2ACYP1A2 | |
| SCHEMBL8517784 | 0.84 | TLR8 (0.44) | ALDH1A1MEN1KMT2ATSHRCYP1A2 | |
| SCHEMBL8375164 | 0.81 | SMPD1 (0.49) | SMPD1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL5328712 | 0.81 | NPC1 (0.53) | SMPD1ALDH1A1SLC5A1MEN1MAPT | |
| SCHEMBL11541209 | 0.81 | ALDH1A1 (0.55) | SMPD1ALDH1A1SLC5A1MEN1MAPT | |
| SCHEMBL8374724 | 0.81 | MAPT (0.47) | MAPTKMT2ANR1H3GAATLR8 | |
| SCHEMBL23400225 | 0.80 | SMPD1 (0.48) | SMPD1ALDH1A1SLC5A1MEN1MAPT | |
| SCHEMBL5328707 | 0.80 | SMPD1 (0.45) | SMPD1ALDH1A1SLC5A1MEN1MAPT | |
| SCHEMBL7371813 | 0.77 | CYP1A2 (0.47) | ALDH1A1MAPTKMT2ACYP1A2CYP3A4 | |
| SCHEMBL8374661 | 0.76 | HSD17B10 (0.43) | ALDH1A1MAPTSMN1; SMN2GAATLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900206-A1 | NEW DIAMINO PYRAZOLS, THEIR SYNTHESIS, KERATIN FIBRE DYEING COMPOSITIONS CONTAINING THEM, KERATIN FIBRE DYEING METHODS | L'OREAL (FR) | 1999-03-10 | — | — | EP | claimed |
| WO-1997042173-A1 | NEW DIAMINO PYRAZOLS, THEIR SYNTHESIS, KERATIN FIBRE DYEING COMPOSITIONS CONTAINING THEM, KERATIN FIBRE DYEING METHODS | L'OREAL (FR) | 1997-11-13 | — | — | WO | claimed |