Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TGM2 | P21980 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11037418 | 0.84 | TSHR (0.46) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL2608211 | 0.81 | ZDHHC20 (0.46) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL18843229 | 0.80 | ALDH1A1 (0.39) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL12314775 | 0.78 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL18843228 | 0.78 | ALDH1A1 (0.37) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL13196125 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL8375422 | 0.77 | ALDH1A1 (0.52) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL2608212 | 0.77 | ZDHHC20 (0.54) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL12556801 | 0.76 | MAPT (0.38) | ALDH1A1TSHRHDAC2GAASMN1; SMN2 | |
| SCHEMBL2608215 | 0.75 | ZDHHC20 (0.57) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883211-A | Thermoreversible hydrogels comprising linear copolymers and their use in electrophoresis | ACLARA BIOSCIENCES, INC. (US) | 1999-03-16 | — | — | US | disclosed |
| WO-1997040078-A1 | THERMOREVERSIBLE HYDROGELS COMPRISING NON-CROSSLINKED COPOLYMERS AND THEIR USE IN ELECTROPHORESIS | SOANE BIOSCIENCES (US) | 1997-10-30 | — | — | WO | disclosed |