Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11740839 | 0.84 | ALDH1A1 (0.59) | ACP1L3MBTL1ALDH1A1KDM4EGAA | |
| Hydrochloric Acid SCHEMBL11736553 | 0.83 | ALDH1A1 (0.61) | ACP1L3MBTL1ALDH1A1KDM4EGAA | |
| SCHEMBL8379657 | 0.79 | ACP1 (0.54) | ACP1L3MBTL1ALDH1A1KDM4EGAA | |
| SCHEMBL8706006 | 0.74 | ACP1 (0.48) | ACP1L3MBTL1ALDH1A1KDM4EGAA | |
| SCHEMBL16453878 | 0.74 | ACP1 (0.48) | ACP1L3MBTL1SMN1; SMN2TP53HTR3A | |
| SCHEMBL1084907 | 0.70 | KDM4E (0.63) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL11735143 | 0.69 | KDM4E (0.52) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL8700137 | 0.67 | PDE5A (0.46) | ACP1ALDH1A1KDM4EGAAGLA | |
| SCHEMBL24649607 | 0.66 | ACP1 (0.66) | ACP1L3MBTL1ALDH1A1KDM4EGAA | |
| SCHEMBL4912408 | 0.66 | SMN1; SMN2 (0.53) | ACP1L3MBTL1ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874438-A | A DRUG TREATING BRAIN DISORDERS, DISEASES OF CENTRAL NERVOUS SYSTEM, DEMENTIA, DEPRESSION, MYOTONIC DYSTROPHY, ASTHMA | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-23 | — | — | US | disclosed |