Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.49 |
| ▸ | HTR3A | P46098 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11740839 | 0.86 | ALDH1A1 (0.59) | ACP1L3MBTL1HSD17B10HPGDGLA | |
| Hydrochloric Acid SCHEMBL11736553 | 0.85 | ALDH1A1 (0.61) | ACP1L3MBTL1HSD17B10HPGDGLA | |
| SCHEMBL8706006 | 0.83 | ACP1 (0.48) | ACP1L3MBTL1HSD17B10HPGDGLA | |
| SCHEMBL8375410 | 0.82 | HRH4 (0.62) | TSHRKDM4EALDH1A1HRH4HTR3A | |
| SCHEMBL16453878 | 0.81 | ACP1 (0.48) | ACP1L3MBTL1HRH4HTR3ATP53 | |
| SCHEMBL3641988 | 0.80 | L3MBTL1 (0.57) | L3MBTL1HSD17B10HPGDGLAGAA | |
| SCHEMBL8375433 | 0.79 | ACP1 (0.46) | ACP1L3MBTL1HSD17B10HPGDGLA | |
| SCHEMBL1084351 | 0.78 | L3MBTL1 (0.63) | ACP1L3MBTL1HSD17B10HPGDGLA | |
| SCHEMBL8700137 | 0.75 | PDE5A (0.46) | ACP1HSD17B10GLAGAATSHR | |
| SCHEMBL3640157 | 0.75 | PDE5A (0.56) | L3MBTL1HSD17B10HPGDGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874438-A | A DRUG TREATING BRAIN DISORDERS, DISEASES OF CENTRAL NERVOUS SYSTEM, DEMENTIA, DEPRESSION, MYOTONIC DYSTROPHY, ASTHMA | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-23 | — | — | US | disclosed |