Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28027637 | 0.89 | MAOA (0.55) | MAOAMAOBTAAR1HTR2AHTR2C | |
| SCHEMBL9406263 | 0.88 | MAOA (0.40) | MAOAMAOBHTR2AHTR2CGRM2 | |
| SCHEMBL9406269 | 0.88 | MAOA (0.40) | MAOAMAOBHTR2AHTR2CGRM2 | |
| SCHEMBL4049556 | 0.87 | MAOA (0.62) | MAOAMAOBTAAR1HTR2AHTR2C | |
| SCHEMBL10715641 | 0.84 | MAOA (0.51) | MAOAMAOBTAAR1HTR2AHTR2C | |
| SCHEMBL8983091 | 0.84 | MAOA (0.38) | MAOAMAOBHTR2AHTR2CGRM2 | |
| SCHEMBL8983100 | 0.84 | MAOA (0.38) | MAOAMAOBHTR2AHTR2CGRM2 | |
| SCHEMBL14433992 | 0.83 | MAOA (0.51) | MAOAMAOBTAAR1HTR2AHTR2C | |
| SCHEMBL9251341 | 0.83 | MEN1 (0.39) | MAOAMAOBGRM2BCHEHRH3 | |
| SCHEMBL9251351 | 0.83 | MEN1 (0.39) | MAOAMAOBGRM2BCHEHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958290-A | ELECTROOPTICAL APPARATUS WITH DIELECTRIC LIQUID CRYSTALS FOR RADIATION TRANSPARENT MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-09-28 | — | — | US | disclosed |
| US-5344587-A | Nitriles | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-09-06 | — | — | US | disclosed |