Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.54 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.54 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.54 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8375716 | 1.00 | SLC9A1 (0.54) | SLC9A1SLC9A3SLC9A2F10AKR1C3 | |
| SCHEMBL19341322 | 0.90 | KMT2A (0.46) | SLC9A1SLC9A3SLC9A2F10AKR1C3 | |
| SCHEMBL13286023 | 0.89 | SLC9A3 (0.74) | SLC9A1SLC9A3SLC9A2F10AKR1C3 | |
| SCHEMBL5426989 | 0.89 | AKR1C3 (0.55) | SLC9A1SLC9A3SLC9A2AKR1C3RAB9A | |
| SCHEMBL5426994 | 0.89 | AKR1C3 (0.55) | SLC9A1SLC9A3SLC9A2AKR1C3RAB9A | |
| SCHEMBL19341326 | 0.87 | KMT2A (0.48) | SLC9A1SLC9A3SLC9A2RAB9ASMN1; SMN2 | |
| SCHEMBL1277382 | 0.81 | KMT2A (0.40) | AKR1C3RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL1277207 | 0.80 | HSD17B1 (0.42) | F10DHODHTRPM8 | |
| SCHEMBL1277376 | 0.79 | F10 (0.35) | SLC9A1SLC9A3SLC9A2F10RAB9A | |
| SCHEMBL24971848 | 0.78 | SLC9A3 (0.74) | SLC9A1SLC9A3SLC9A2F10AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901788-A2 | Use of inhibitors of the sodium hydrogen exchange in the manufacture of a medicament | Hoechst Marion Roussel Deutschland GmbH (DE) | 1999-03-17 | — | — | EP | claimed |
| EP-0901788-A2 | Use of inhibitors of the sodium hydrogen exchange in the manufacture of a medicament | Hoechst Marion Roussel Deutschland GmbH (DE) | 1999-03-17 | — | — | EP | disclosed |