Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4593967 | 0.87 | EPHX1 (0.41) | EPHX1TRPM8TRPA1ALDH1A1TSHR | |
| SCHEMBL29450387 | 0.85 | EPHX1 (0.44) | EPHX1TRPM8TRPA1ALDH1A1CYP19A1 | |
| SCHEMBL4594644 | 0.85 | EPHX1 (0.44) | EPHX1TRPM8TRPA1ALDH1A1CYP19A1 | |
| SCHEMBL4251270 | 0.85 | TRPM8 (0.46) | EPHX1TRPM8TRPA1ALDH1A1MAPT | |
| SCHEMBL9410240 | 0.82 | EPHX1 (0.44) | EPHX1TRPM8TRPA1ALDH1A1MAPT | |
| SCHEMBL3274995 | 0.80 | EPHX1 (0.47) | EPHX1TRPM8TRPA1CYP19A1 | |
| SCHEMBL19809107 | 0.79 | EPHX1 (0.41) | EPHX1TRPM8TRPA1ALDH1A1MAPT | |
| SCHEMBL9951572 | 0.78 | EPHX1 (0.51) | EPHX1TRPM8TRPA1CYP19A1 | |
| SCHEMBL457824 | 0.78 | EPHX1 (0.51) | EPHX1TRPM8TRPA1CYP19A1 | |
| SCHEMBL1253937 | 0.78 | EPHX1 (0.45) | EPHX1TRPM8TRPA1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790883-B1 | SKIN ENGAGING MEMBER | GILLETTE CO (US) | 1999-03-31 | — | — | EP | claimed |
| EP-0837759-B1 | WET SHAVING SYSTEM WITH SHAVING AID COMPOSITE WITH A NON-VOLATILE COOLING AGENT | GILLETTE CO (US) | 1999-03-03 | — | — | EP | claimed |
| EP-0837760-B1 | WET SHAVINGSYSTEM WITH SHAVING AID COMPOSITE WITH AN INCLUSION COMPLEX OF A SKIN-SOOTHING AGENT AND CYCLODEXTRIN | GILLETTE CO (US) | 1999-02-10 | — | — | EP | claimed |