SCHEMBL9951572

SCHEMBL9951572

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nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 3/20 0.51
TRPM8 Q7Z2W7 4/20 0.50
TRPA1 O75762 2/20 0.50
SLC6A12 P48065 3/20 0.41
SLC6A11 P48066 3/20 0.41
SLC6A13 Q9NSD5 3/20 0.41
SLC1A2 P43004 2/20 0.40
MEN1 O00255 1/20 0.40
CYP1A2 P05177 1/20 0.40
ALOX15 P16050 1/20 0.40
KMT2A Q03164 1/20 0.40
KCNA5 P22460 1/20 0.40
TRPV1 Q8NER1 2/20 0.39
CYP19A1 P11511 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL457824 1.00 EPHX1 (0.51) EPHX1TRPM8TRPA1SLC6A12SLC6A11
Formaldehyde SCHEMBL31298519 0.96 EPHX1 (0.49) EPHX1TRPM8TRPA1SLC6A12SLC6A11
Acetic Acid SCHEMBL30541669 0.96 EPHX1 (0.49) EPHX1TRPM8TRPA1SLC6A12SLC6A11
SCHEMBL3855216 0.86 EPHX1 (0.50) EPHX1TRPM8TRPA1TRPV1
SCHEMBL11291061 0.86 EPHX1 (0.49) EPHX1TRPM8TRPA1KCNA5TRPV1
SCHEMBL29992331 0.85 EPHX1 (0.49) EPHX1MEN1KMT2ACYP19A1
SCHEMBL29450749 0.85 EPHX1 (0.49) EPHX1MEN1KMT2ACYP19A1
SCHEMBL29590959 0.85 EPHX1 (0.49) EPHX1MEN1KMT2ACYP19A1
SCHEMBL9951688 0.85 EPHX1 (0.51) EPHX1TRPM8TRPA1TRPV1CYP19A1
SCHEMBL9951381 0.85 EPHX1 (0.51) EPHX1TRPM8TRPA1TRPV1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025045354-A1 A FRAGRANCE TABLET SYMRISE AG (DE) 2025-03-06 WO claimed
WO-2025045353-A1 A FRAGRANCE POD SYMRISE AG (DE) 2025-03-06 WO claimed
WO-2026046686-A1 EVAPORATING MICROEMULSIONS SYMRISE AG (DE) 2026-03-05 WO disclosed
WO-2026046506-A1 EVAPORATING MICROEMULSIONS SYMRISE AG (DE) 2026-03-05 WO disclosed
EP-4623057-A1 ENCAPSULATED FRAGRANCE COMPOSITIONS FOR PROVIDING, MODULATING OR INTENSIFYING A SCENT Symrise AG (DE) 2025-10-01 EP disclosed
WO-2025119505-A1 ENCAPSULATED FRAGRANCE COMPOSITIONS FOR PROVIDING, MODULATING OR INTENSIFYING A SCENT SYMRISE AG (DE) 2025-06-12 WO disclosed
WO-2025051340-A1 TRPM8 MODULATORS AND RELATED METHOD FOR MODULATING TRPM8 RECEPTORS SYMRISE AG (DE) 2025-03-13 WO disclosed
CN-114502138-A Improvements in or relating to organic compounds 奇华顿股份有限公司 2022-05-13 CN disclosed
US-20120165559-A1 Compounds Having a Physiological Effect V. MANE FILS (FR) 2012-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120165559-A1 Compounds Having a Physiological Effect NPPA, CYP11B2, SHBG EPHX1 871/4885TRPM8 412/4885TRPA1 418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.