Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8376477 | 0.86 | TSHR (0.42) | TSHRCYP1A2TDP1CYP2C19CYP2C9 | |
| SCHEMBL8379857 | 0.81 | TSHR (0.46) | TSHRCYP1A2CYP2C19CYP2C9KIF11 | |
| SCHEMBL7409166 | 0.80 | TSHR (0.50) | TSHRCYP1A2TDP1CYP2C19CYP2C9 | |
| SCHEMBL28790232 | 0.79 | TSHR (0.44) | TSHRCYP1A2TDP1CYP2C19CYP2C9 | |
| SCHEMBL11814132 | 0.78 | TSHR (0.48) | TSHRCYP1A2CYP2C19CYP2C9KIF11 | |
| SCHEMBL2102354 | 0.78 | TSHR (0.48) | TSHRCYP1A2CYP2C19CYP2C9KIF11 | |
| SCHEMBL9618238 | 0.76 | KIF11 (0.50) | TSHRCYP1A2CYP2C19CYP2C9KIF11 | |
| SCHEMBL6680627 | 0.76 | TSHR (0.46) | TSHRCYP1A2CYP2C19CYP2C9KIF11 | |
| SCHEMBL27491062 | 0.76 | TSHR (0.46) | TSHRCYP1A2TDP1CYP2C19CYP2C9 | |
| SCHEMBL8166179 | 0.76 | CYP1A2 (0.48) | TSHRCYP1A2CYP2C19KIF11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108379686-B | Non-packaging syringe assembly with sterilizable fluid path | 贝克顿·迪金森公司 | 2020-10-16 | — | — | CN | disclosed |
| US-6005116-A | HAVE INHIBITION ACTIVITIES AGAINST TYPE A-MONOAMINE OXIDASE; TREATING OR PREVENTING DEPRESSION, PARKINSON'S DISEASE, ALZEHEIMER'S DEMENTIA, OR CEREBROVASCULAR DEMENTIA | SANKYO COMPANY, LIMITED (JP) | 1999-12-21 | — | — | US | disclosed |
| EP-0885891-A1 | ISOXAZOLE DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |